IpiRecord: IPI00194045

IPI00194045 - Idh1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC.
Uniprot Accession: Q0QER8
Uniprot ID: Q0QER8_RAT
Mapping: Chr 9, 63769401 - 63790622
Entrez Gene: 24479
Entrez MapView: Geneprod
RGD: 2862
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8812)
Rat: Idh1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC.
Mouse: Idh1, FULL INSERT SEQUENCE.
Mouse: Idh1, CLONE:I830026O07 PRODUCT:ISOCITRATE DEHYDROGENASE 1.
Mouse: Idh1, 16 KDA PROTEIN.
Rat: Idh1, 50 KDA PROTEIN.
Human: IDH1, NADP+-SPECIFIC ISOCITRATE DEHYDROGENASE (FRAGMENT).
Human: IDH1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC.

Annotations for Idh1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IEA 
cytosolCTAS IDA ISS ISS 
soluble fractionCIDA 
peroxisomeCIEA IDA 
NADP bindingFIDA 
metal ion bindingFIEA 
isocitrate dehydrogenase (NADP+) activityFIEA TAS IDA IDA TAS ISS ISS IEA IDA 
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorFIEA IEA IEA 
manganese ion bindingFIEA IEA IEA 
magnesium ion bindingFIEA IEA IEA 
oxidoreductase activityFIEA IEA IEA 
glutathione metabolic processPIEA IMP ISS 
metabolic processPIEA IEA IEA 
response to oxidative stressPIEA IDA ISS 
carbohydrate metabolic processPTAS ISS 
tricarboxylic acid cyclePIEA IEA IEA 
glyoxylate cyclePIEA IEA IEA 
isocitrate metabolic processPTAS ISS IDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
ObesityDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
citrate cycle pathwayWIEA
glutathione metabolic pathwayWIEA
reductive carboxylate cycle - CO2 fixation pathwayWIEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glutathione metabolism (00480)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Reductive carboxylate cycle (CO2 fixation) (00720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway