| IPI00194045 - Idh1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC. | |
|---|---|
| Uniprot Accession: Q0QER8 | |
| Uniprot ID: Q0QER8_RAT | |
| Mapping: Chr 9, 63769401 - 63790622 | |
| Entrez Gene: 24479 | |
| Entrez MapView: |
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| RGD: 2862 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8812) |
|---|
| Rat: Idh1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC. |
| Mouse: Idh1, FULL INSERT SEQUENCE. |
| Mouse: Idh1, CLONE:I830026O07 PRODUCT:ISOCITRATE DEHYDROGENASE 1. |
| Mouse: Idh1, 16 KDA PROTEIN. |
| Rat: Idh1, 50 KDA PROTEIN. |
| Human: IDH1, NADP+-SPECIFIC ISOCITRATE DEHYDROGENASE (FRAGMENT). |
| Human: IDH1, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | IEA | |
| cytosol | C | TAS | IDA | ISS ISS |
| soluble fraction | C | IDA | ||
| peroxisome | C | IEA | IDA | |
| NADP binding | F | IDA | ||
| metal ion binding | F | IEA | ||
| isocitrate dehydrogenase (NADP+) activity | F | IEA TAS | IDA IDA | TAS ISS ISS IEA IDA |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | F | IEA | IEA | IEA |
| manganese ion binding | F | IEA | IEA | IEA |
| magnesium ion binding | F | IEA | IEA | IEA |
| oxidoreductase activity | F | IEA | IEA | IEA |
| glutathione metabolic process | P | IEA | IMP | ISS |
| metabolic process | P | IEA | IEA | IEA |
| response to oxidative stress | P | IEA | IDA | ISS |
| carbohydrate metabolic process | P | TAS | ISS | |
| tricarboxylic acid cycle | P | IEA | IEA | IEA |
| glyoxylate cycle | P | IEA | IEA | IEA |
| isocitrate metabolic process | P | TAS | ISS IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Obesity | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| citrate cycle pathway | W | IEA | ||
| glutathione metabolic pathway | W | IEA | ||
| reductive carboxylate cycle - CO2 fixation pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glutathione metabolism (00480) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Citrate cycle (TCA cycle) (00020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Reductive carboxylate cycle (CO2 fixation) (00720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |