IpiRecord: IPI00195173

IPI00195173 - Cd59, CD59 GLYCOPROTEIN PRECURSOR.
Uniprot Accession: P27274
Uniprot ID: CD59_RAT
Mapping: Chr , -
Entrez Gene: 25407
Entrez MapView: Geneprod
RGD: 2311
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3606)
Rat: Cd59, CD59 GLYCOPROTEIN PRECURSOR.
Mouse: Cd59b, CD59B GLYCOPROTEIN PRECURSOR.
Mouse: Cd59b, CD59B.
Mouse: Cd59b, CD59B PROTEIN.
Mouse: Cd59b, CD59B ANTIGEN.
Human: CD59, CD59 GLYCOPROTEIN PRECURSOR.
Human: CD59, 13 KDA PROTEIN.

Annotations for Cd59 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCNAS IDA ISS 
compact myelinCIDA 
extracellular spaceCISS IDA 
membrane fractionCTAS ISS 
membraneCIEA IEA 
cell surfaceCIDA 
sarcolemmaCIDA 
GPI anchor bindingFIEA IEA IEA 
protein bindingFIPI ISS IDA 
immune responsePNR ISS 
negative regulation of complement activationPIDA 
defense responsePNR 
negative regulation of cytolysisPIDA 
cell surface receptor linked signal transductionPTAS ISS 
negative regulation of activation of membrane attack complexPIDA IDA 
positive regulation of T cell proliferationPIMP 
anti-apoptosisPIMP 
blood coagulationPTAS ISS 
regulation of complement activationPNAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
renal/urinary system phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn

Disease (12)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Pancreatitis, Acute NecrotizingDIEP
Myocardial InfarctionDIEP
GlomerulonephritisDIMP
NephrosisDIMP
Neuritis, Experimental AllergicDIEP
Liver Diseases, AlcoholicDIEP
Diabetic RetinopathyDIEP
Arthritis, ExperimentalDIED
Facial Nerve InjuriesDIEP
Reperfusion InjuryDIED
Colonic NeoplasmsDIMP
Uveitis, AnteriorDIED

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Complement and coagulation cascades (04610)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway