| IPI00195456 - Acvr1b, ACTIVIN RECEPTOR TYPE-1B PRECURSOR. | |
|---|---|
| Uniprot Accession: P80202 | |
| Uniprot ID: ACV1B_RAT | |
| Mapping: Chr 7, 139937993 - 139958724 | |
| Entrez Gene: 29381 | |
| Entrez MapView: |
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| RGD: 735207 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7451) |
|---|
| Rat: Acvr1b, ACTIVIN RECEPTOR TYPE-1B PRECURSOR. |
| Mouse: Acvr1b, ACTIVIN RECEPTOR TYPE-1B PRECURSOR. |
| Human: ACVR1B, ISOFORM 1 OF ACTIVIN RECEPTOR TYPE-1B PRECURSOR. |
| Human: ACVR1B, ISOFORM 2 OF ACTIVIN RECEPTOR TYPE-1B PRECURSOR. |
| Human: ACVR1B, ISOFORM 3 OF ACTIVIN RECEPTOR TYPE-1B PRECURSOR. |
| Human: ACVR1B, 8 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cell surface | C | IEA | ||
| membrane | C | RCA | ISS IEA | |
| activin receptor complex | C | ISS IMP | ||
| integral to plasma membrane | C | TAS | ISS ISS IEA | |
| extracellular space | C | ISS | ||
| integral to membrane | C | RCA | ISS | |
| kinase activity | F | IEA | ||
| activin binding | F | IPI | ISS IEA | |
| SMAD binding | F | IMP IEA | ||
| metal ion binding | F | IEA | ||
| growth factor binding | F | IEA | ||
| protein kinase activity | F | RCA | ISS | |
| protein-tyrosine kinase activity | F | ISS | ||
| protein serine/threonine kinase activity | F | IEA | IEA IEA | IEA |
| manganese ion binding | F | IEA | IEA | |
| activin receptor activity, type I | F | TAS IMP | ||
| transmembrane receptor protein serine/threonine kinase activity | F | TAS | TAS ISS | |
| receptor signaling protein serine/threonine kinase activity | F | IMP | ||
| receptor activity | F | IEA | IEA | |
| transferase activity | F | IEA | IEA | |
| transforming growth factor beta receptor activity | F | RCA | ISS IEA | |
| magnesium ion binding | F | IEA | IEA | |
| transforming growth factor beta receptor activity, type I | F | ISS | ||
| ATP binding | F | IEA | IEA IEA | IEA |
| nucleotide binding | F | IEA | IEA | |
| protein amino acid phosphorylation | P | IEA | RCA | TAS ISS IMP IEA |
| in utero embryonic development | P | IMP IMP | ISS IEA | |
| negative regulation of cell growth | P | IEA | ||
| G1/S transition of mitotic cell cycle | P | IEA | ||
| induction of apoptosis | P | IEA | ||
| positive regulation of erythrocyte differentiation | P | IEA | ||
| hair follicle development | P | IMP | IEA | |
| embryonic development | P | IMP | ISS IEA | |
| cell surface receptor linked signal transduction | P | TAS | ISS | |
| regulation of transcription | P | IEA | ||
| signal transduction | P | IEA | ||
| transmembrane receptor protein serine/threonine kinase signaling pathway | P | ISS | ||
| mesoderm development | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Pancreatic Neoplasms | D | ISS | ||
| Myocardial Ischemia | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| activin signaling pathway | W | TAS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |