| IPI00198519 - Abcb4, MULTIDRUG RESISTANCE PROTEIN 2. | |
|---|---|
| Uniprot Accession: Q64714 | |
| Uniprot ID: Q64714_RAT | |
| Mapping: Chr 4, 21946113 - 22147328 | |
| Entrez Gene: 24891 | |
| Entrez MapView: |
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| RGD: 620248 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4243) |
|---|
| Rat: Abcb4, MULTIDRUG RESISTANCE PROTEIN 2. |
| Mouse: Abcb4, MULTIDRUG RESISTANCE PROTEIN 2. |
| Mouse: Abcb4, MEMBER 4, FULL INSERT SEQUENCE (FRAGMENT). |
| Rat: Abcb4, 15 KDA PROTEIN. |
| Human: ABCB4, ATP-BINDING CASSETTE, SUBFAMILY B, MEMBER 4 ISOFORM C. |
| Human: ABCB4, ISOFORM 1 OF MULTIDRUG RESISTANCE PROTEIN 3. |
| Human: ABCB4, ISOFORM 2 OF MULTIDRUG RESISTANCE PROTEIN 3. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| intercellular canaliculus | C | IDA | ISS | |
| membrane | C | IEA | IEA | |
| cellular_component | C | ND | ||
| integral to membrane | C | RCA | ISS IEA | |
| membrane fraction | C | IDA | ||
| apical plasma membrane | C | IDA | ||
| Golgi membrane | C | IDA | ||
| ATPase activity, coupled to transmembrane movement of substances | F | IEA | ||
| ATP binding | F | IEA IEA | IEA | |
| nucleoside-triphosphatase activity | F | IEA | ||
| hydrolase activity | F | IEA | IEA | |
| nucleic acid binding | F | ISS | ||
| protein binding | F | IPI IPI | ||
| xenobiotic-transporting ATPase activity | F | IEA | IEA | |
| nucleotide binding | F | IEA IEA | IEA | |
| ATPase activity | F | IEA | IEA | |
| transport | P | IEA IEA | IEA | |
| response to glucocorticoid stimulus | P | IEP | ||
| response to drug | P | IEP | ||
| response to xenobiotic stimulus | P | NAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cholestasis, Intrahepatic | D | ISS | ||
| Cholestasis | D | IEP | ||
| Diabetes Mellitus, Experimental | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| multidrug resistance protein mediated transport pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |