IpiRecord: IPI00199035

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C	IDA TAS
PDZ domain binding	F	IPI IPI
protein binding	F	IPI IPI IPI	IPI
protein serine/threonine phosphatase activity	F	IDA
phosphoric monoester hydrolase activity	F		IEA	IEA
inositol or phosphatidylinositol phosphatase activity	F			ISS
platelet-derived growth factor receptor binding	F			IDA
lipid binding	F	IEA
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	F	IDA
hydrolase activity	F	IEA	IEA	IEA
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity	F	IDA
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	F	IDA IDA	IDA	ISS
protein tyrosine phosphatase activity	F	IDA
protein tyrosine/serine/threonine phosphatase activity	F	IEA	IEA	TAS IEA
phosphatidylinositol-3-phosphatase activity	F	IDA
negative regulation of cell proliferation	P	IMP	IGI IMP	IDA
phosphoinositide dephosphorylation	P	IDA IDA
inositol phosphate dephosphorylation	P	IDA		ISS
platelet-derived growth factor receptor signaling pathway	P			IDA
endothelial cell migration	P	IEA	IMP
lipid metabolic process	P	IEA
dephosphorylation	P		IEA
negative regulation of progression through cell cycle	P	IEA	IEA
protein amino acid dephosphorylation	P	IDA TAS	IEA	IEA
negative regulation of apoptosis	P	IEA	IMP
regulation of protein stability	P	IMP
cell proliferation	P	TAS
regulation of cyclin-dependent protein kinase activity	P	TAS
negative regulation of protein kinase B signaling cascade	P	IMP	IMP
negative regulation of cell migration	P	IMP		TAS
central nervous system development	P	ISS	IMP	ISS
angiogenesis	P	IEA	IMP
cell cycle	P	IEA	IEA
induction of apoptosis	P	ISS	IMP	TAS ISS
negative regulation of focal adhesion formation	P	IMP
heart development	P	ISS	IMP	ISS
neurite development	P			IDA
cell migration	P		IMP	ISS
cardiac muscle development	P	IEA	IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (34)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
craniofacial phenotype	MP		Un
adipose tissue phenotype	MP		Un
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un Un Un
growth/size phenotype	MP		Un Un
immune system phenotype	MP		Un Un Un
embryogenesis phenotype	MP		Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un Un Un
life span-post-weaning/aging	MP		Un Un Un
reproductive system phenotype	MP		Un Un Un Un Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un Un Un
hematopoietic system phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un Un
normal phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un
tumorigenesis	MP		Un Un Un Un Un Un
epidermal hyperplasia	N			ISS
abnormal brain development	N			ISS
embryonic growth arrest	N			ISS
seizures	N			ISS
embryonic lethality	N			ISS
fatty liver	N			ISS
skin hyperplasia	N			ISS
prostate gland hyperplasia	N			ISS
resistance to tumor development	N			ISS
enlarged liver	N			ISS
decreased cardiac muscle contractility	N			ISS
ataxia	N			ISS
cardiac hypertrophy	N			ISS
increased B cell proliferation	N			ISS

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypertrophy, Left Ventricular	D			IED
Cardiomegaly	D			ISS
Hypertension, Portal	D			IED

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
inositol phosphate metabolic pathway	W			IEA
phosphatidylinositol 3 kinase-Akt signaling pathway	W			IEA

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Tight junction (04530)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Inositol phosphate metabolism (00562)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Phosphatidylinositol signaling system (04070)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway