IpiRecord: IPI00199609

IPI00199609 - Ide, INSULIN-DEGRADING ENZYME.
Uniprot Accession: P35559
Uniprot ID: IDE_RAT
Mapping: Chr 1, 241547869 - 241646052
Entrez Gene: 25700
Entrez MapView: Geneprod
RGD: 2861
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1839)
Rat: Ide, INSULIN-DEGRADING ENZYME.
Mouse: Ide, INSULIN-DEGRADING ENZYME.
Mouse: Ide, SEQUENCE (FRAGMENT).
Mouse: Ide, INSULIN DEGRADING ENZYME.
Human: IDE, INSULIN-DEGRADING ENZYME.
Human: IDE, INSULIN-DEGRADING ENZYME.

Annotations for Ide and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IEA 
peroxisomeCTAS ISS ISS 
extracellular spaceCTAS RCA ISS ISS 
soluble fractionCTAS ISS 
hydrolase activityFIEA 
signal transducer activityFTAS TAS ISS 
insulysin activityFTAS IEA TAS ISS IEA 
metallopeptidase activityFIEA 
peptidase activityFIEA TAS 
metal ion bindingFIEA IEA IEA 
catalytic activityFIEA 
metalloendopeptidase activityFIEA IEA 
zinc ion bindingFIEA IEA IEA IEA 
sex differentiationPTAS ISS 
cell-cell signalingPNR ISS 
peptide catabolic processPTAS 
signal transductionPNAS ISS 
proteolysisPTAS IEA IEA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
other phenotypeMPUn
normal phenotypeMPUn
nervous system phenotypeMPUn
amyloidosisNISS

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Diabetes Mellitus, Non-Insulin-DependentDISSISS
Alzheimer DiseaseDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway