IpiRecord: IPI00199614

IPI00199614 - Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Uniprot Accession: P58428-1
Uniprot ID: ABCG8_RAT
Mapping: Chr 6, 8064741 - 8080571
Entrez Gene: 155192
Entrez MapView: Geneprod
RGD: 620300
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6107)
Rat: Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Mouse: Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Mouse: Abcg8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Rat: Abcg8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Rat: Abcg8, ISOFORM 3 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Rat: Abcg8, 77 KDA PROTEIN.
Human: ABCG8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.
Human: ABCG8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8.

Annotations for Abcg8 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to membraneCRCA ISS 
ATP-binding cassette (ABC) transporter complexCTAS 
membraneCIEA 
cholesterol transporter activityFTAS 
nucleotide bindingFIEA 
ATP bindingFIEA IEA 
ATPase activityFIEA 
sterol transporter activityFIMP 
sterol metabolic processPISS 
response to nutrientPIEP 
cholesterol transportPTAS 
transportPIEA 
regulation of cholesterol absorptionPTAS 
sterol transportPTAS 
response to drugPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
liver/biliary system phenotypeMPUn
increased cholesterol absorptionNISS

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CholestasisDIEP
HypercholesterolemiaDISS
ObesityDISS
Diabetes Mellitus, ExperimentalDIEP
ArteriosclerosisDISS
HyperlipidemiaDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway