| IPI00199614 - Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. | |
|---|---|
| Uniprot Accession: P58428-1 | |
| Uniprot ID: ABCG8_RAT | |
| Mapping: Chr 6, 8064741 - 8080571 | |
| Entrez Gene: 155192 | |
| Entrez MapView: |
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| RGD: 620300 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6107) |
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| Rat: Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Mouse: Abcg8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Mouse: Abcg8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Rat: Abcg8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Rat: Abcg8, ISOFORM 3 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Rat: Abcg8, 77 KDA PROTEIN. |
| Human: ABCG8, ISOFORM 1 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| Human: ABCG8, ISOFORM 2 OF ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to membrane | C | RCA | ISS | |
| ATP-binding cassette (ABC) transporter complex | C | TAS | ||
| membrane | C | IEA | ||
| cholesterol transporter activity | F | TAS | ||
| nucleotide binding | F | IEA | ||
| ATP binding | F | IEA IEA | ||
| ATPase activity | F | IEA | ||
| sterol transporter activity | F | IMP | ||
| sterol metabolic process | P | ISS | ||
| response to nutrient | P | IEP | ||
| cholesterol transport | P | TAS | ||
| transport | P | IEA | ||
| regulation of cholesterol absorption | P | TAS | ||
| sterol transport | P | TAS | ||
| response to drug | P | IEP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un | ||
| increased cholesterol absorption | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cholestasis | D | IEP | ||
| Hypercholesterolemia | D | ISS | ||
| Obesity | D | ISS | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Arteriosclerosis | D | ISS | ||
| Hyperlipidemia | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |