IpiRecord: IPI00199853

IPI00199853 - Itgam, INTEGRIN BETA 2 ALPHA SUBUNIT.
Uniprot Accession: Q9JI30
Uniprot ID: Q9JI30_RAT
Mapping: Chr 1, 187334413 - 187385583
Entrez Gene: 25021
Entrez MapView: Geneprod
RGD: 2926
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1241)
Rat: Itgam, INTEGRIN BETA 2 ALPHA SUBUNIT.
Mouse: Itgam, SEQUENCE.
Mouse: Itgam, ISOFORM 2 OF INTEGRIN ALPHA-M PRECURSOR.
Mouse: Itgam, INTEGRIN ALPHA M ISOFORM 2 PRECURSOR.
Rat: Itgam, INTEGRIN ALPHA-M.
Human: ITGAM, INTEGRIN ALPHA-M PRECURSOR.
Human: ITGAM, INTEGRIN, ALPHA M.
Human: ITGAM, 65 KDA PROTEIN.

Annotations for Itgam and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
external side of plasma membraneCIEA IDA IDA IDA IDA IDA IDA IDA ISS 
integrin complexCTAS IEA IEA IEA 
integral to membraneCIEA IDA ISS IEA 
nucleusCIEA IDA ISS 
membraneCIEA IEA 
protein heterodimerization activityFIPI 
receptor activityFIEA IEA IEA 
opsonin bindingFIEA IDA IMP ISS 
protein bindingFIEA IEA IEA 
glycoprotein bindingFIPI 
calcium ion bindingFIEA IEA 
magnesium ion bindingFIEA 
integrin-mediated signaling pathwayPIEA IEA IEA 
cell adhesionPTAS IEA IMP ISS IEA 
neutrophil chemotaxisPIEA IMP ISS 
activated T cell proliferationPIEA IMP ISS 
cellular extravasationPIEA IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
immune system phenotypeMPUn Un Un
nervous system phenotypeMPUn
hematopoietic system phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
integrin signaling pathwayWISS

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway