| IPI00200583 - Cd4, T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR. | |
|---|---|
| Uniprot Accession: P05540 | |
| Uniprot ID: CD4_RAT | |
| Mapping: Chr 4, 160988512 - 161014038 | |
| Entrez Gene: 24932 | |
| Entrez MapView: |
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| RGD: 2306 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4879) |
|---|
| Rat: Cd4, T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR. |
| Mouse: Cd4, ISOFORM 1 OF T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR. |
| Mouse: Cd4, ISOFORM 2 OF T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR. |
| Mouse: Cd4, MUTANT T-CELL SURFACE GLYCOPROTEIN CD4. |
| Rat: Cd4, 51 KDA PROTEIN. |
| Rat: Cd4, 10 KDA PROTEIN. |
| Human: CD4, T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR. |
| Human: CD4, 8 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| plasma membrane | C | IDA | ISS IDA | ISS ISS |
| external side of plasma membrane | C | IEA | IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA | ISS |
| T cell receptor complex | C | NAS | ISS ISS | |
| membrane | C | IEA IEA | IEA | |
| integral to membrane | C | IEA | RCA | ISS IEA |
| extracellular matrix structural constituent | F | NAS | ISS | |
| glycoprotein binding | F | IPI | ISS | |
| transmembrane receptor activity | F | TAS | ISS | |
| MHC class II protein binding | F | NAS | ISS ISS | |
| protein homodimerization activity | F | IDA | ISS | |
| protein kinase binding | F | IPI | ISS | |
| zinc ion binding | F | IDA | ISS | |
| protein binding | F | IPI | ||
| coreceptor activity | F | NAS | ISS | |
| positive regulation of peptidyl-tyrosine phosphorylation | P | IEA | IDA | ISS |
| positive regulation of T cell activation | P | IEA | IDA | ISS |
| cytokine production | P | IEA | IMP IGI | |
| T cell selection | P | IDA | ISS | ISS ISS |
| positive regulation of calcium-mediated signaling | P | IEA | IDA | ISS |
| cell surface receptor linked signal transduction | P | IDA | ISS | |
| immune response | P | NAS | IEA IEA | ISS IEA |
| cell adhesion | P | IEA | IEA | IEA |
| T cell differentiation | P | ISS | ||
| T cell activation | P | IMP | ||
| conjugation with cellular fusion | P | IDA | ISS | |
| regulation of T cell activation | P | ISS | ||
| positive regulation of protein kinase activity | P | IDA | ISS | |
| positive regulation of interleukin-2 biosynthetic process | P | NAS | ISS ISS | |
| transmembrane receptor protein tyrosine kinase signaling pathway | P | NAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un Un Un Un Un Un | ||
| lethality-postnatal | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un Un Un Un Un | ||
| life span-post-weaning/aging | MP | Un Un | ||
| no phenotypic analysis | MP | Un Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Antigen processing and presentation (04612) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell adhesion molecules (CAMs) (04514) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hematopoietic cell lineage (04640) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |