| IPI00201424 - Prkaa2, ALPHA-2. | |
|---|---|
| Uniprot Accession: Q09137-1 | |
| Uniprot ID: AAPK2_RAT | |
| Mapping: Chr 5, 126007672 - 126074012 | |
| Entrez Gene: 78975 | |
| Entrez MapView: |
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| RGD: 620893 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5560) |
|---|
| Rat: Prkaa2, ALPHA-2. |
| Mouse: Prkaa2, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2. |
| Rat: Prkaa2, ALPHA-2. |
| Human: PRKAA2, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| protein complex | C | IDA | ||
| AMP-activated protein kinase complex | C | IDA IMP | ||
| nucleus | C | IEA | IDA | TAS ISS |
| protein binding, bridging | F | IDA | ||
| protein binding | F | IPI | ||
| AMP-activated protein kinase activity | F | TAS | IDA IMP ISS IMP IDA | |
| protein kinase activity | F | IEA | IDA | |
| kinase activity | F | IEA | ||
| ATP binding | F | IEA | IEA IEA | IDA |
| protein serine/threonine kinase activity | F | IEA | IEA IEA | IDA |
| metal ion binding | F | IEA | ||
| transferase activity | F | IEA | IEA | |
| magnesium ion binding | F | IEA | IEA | |
| nucleotide binding | F | IEA | IEA | |
| protein amino acid phosphorylation | P | TAS | IEA | IDA ISS IDA |
| lipid biosynthetic process | P | IEA | ||
| regulation of lipid metabolic process | P | IDA | ||
| response to stress | P | TAS | IDA ISS | |
| sterol biosynthetic process | P | IEA | ||
| fatty acid biosynthetic process | P | IEA | IEA | |
| cholesterol biosynthetic process | P | IEA | IEA | |
| steroid biosynthetic process | P | IEA | ||
| signal transduction | P | TAS | ISS | |
| protein heterooligomerization | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| impaired glucose tolerance | N | ISS | ||
| insulin resistance | N | ISS | ||
| decreased insulin secretion | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus, Non-Insulin-Dependent | D | ISS | ||
| Insulin Resistance | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nicotinate and nicotinamide metabolic pathway | W | IEA | ||
| inositol phosphate metabolic pathway | W | IEA | ||
| adenosine monophosphate-activated protein kinase (AMPK) signaling pathway | W | IDAISSISS | ||
| starch and sucrose metabolic pathway | W | IEA | ||
| benzoate degradation pathway via CoA ligation | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Regulation of autophagy (04140) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |