| IPI00202227 - Tnfsf10, TNF-RELATED APOPTOSIS INDUCING LIGAND. | |
|---|---|
| Uniprot Accession: Q8K3G0 | |
| Uniprot ID: Q8K3G0_RAT | |
| Mapping: Chr 2, 113204304 - 113221562 | |
| Entrez Gene: 246775 | |
| Entrez MapView: |
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| RGD: 628734 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2326) |
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| Rat: Tnfsf10, TNF-RELATED APOPTOSIS INDUCING LIGAND. |
| Mouse: Tnfsf10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10. |
| Human: TNFSF10, UNCHARACTERIZED PROTEIN TNFSF10. |
| Human: TNFSF10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10. |
| Human: TNFSF10, 6 KDA PROTEIN. |
| Human: TNFSF10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 SPLICE VARIANT. |
| Human: TNFSF10, 14 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | TAS | ||
| membrane | C | IEA | IEA IEA | IEA |
| integral to membrane | C | RCA | ISS | |
| extracellular space | C | IEA | IEA | |
| soluble fraction | C | TAS | ||
| zinc ion binding | F | IEA | ||
| protein binding | F | IPI | ISS | |
| tumor necrosis factor receptor binding | F | IEA | IEA | IEA |
| cytokine activity | F | IEA | IEA | |
| metal ion binding | F | IEA | ||
| signal transducer activity | F | IEP | ||
| apoptosis | P | IEA | IEA IEA | |
| signal transduction | P | TAS TAS | ||
| induction of apoptosis | P | TAS | NAS | |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | P | IEP | ||
| cell-cell signaling | P | TAS | ||
| immune response | P | IEA | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| immune system phenotype | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| tumorigenesis | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |