| IPI00202498 - Pdgfra, ALPHA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR. | |
|---|---|
| Uniprot Accession: P20786 | |
| Uniprot ID: PGFRA_RAT | |
| Mapping: Chr 14, 35369673 - 35418129 | |
| Entrez Gene: 25267 | |
| Entrez MapView: |
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| RGD: 3284 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12137) |
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| Rat: Pdgfra, ALPHA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR. |
| Mouse: Pdgfra, ALPHA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR. |
| Mouse: Pdgfra, PLATELET DERIVED GROWTH FACTOR RECEPTOR, ALPHA POLYPEPTIDE. |
| Rat: Pdgfra, 55 KDA PROTEIN. |
| Rat: Pdgfra, (PDGF-R-ALPHA) ISOFORM 1. |
| Human: PDGFRA, PRECURSOR. |
| Human: PDGFRA, PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | ISS | ||
| integral to membrane | C | IEA | IEA | |
| membrane | C | IEA IEA | IEA | |
| platelet-derived growth factor alpha-receptor activity | F | IDA TAS ISS | ||
| protein-tyrosine kinase activity | F | IEA IEA | ||
| ATP binding | F | IEA IEA | IEA | |
| protein serine/threonine kinase activity | F | ISS | ||
| receptor activity | F | IEA | IEA | |
| kinase activity | F | IEA | ||
| platelet-derived growth factor binding | F | IDA | ISS | |
| transmembrane receptor protein tyrosine kinase activity | F | IEA | ||
| nucleotide binding | F | IEA | IEA | |
| protein dimerization activity | F | NAS | ||
| protein kinase activity | F | IEA | ||
| vascular endothelial growth factor receptor activity | F | IEA | IEA | |
| transferase activity | F | IEA | IEA | |
| gliogenesis | P | IEP NAS | ||
| cell proliferation | P | ISS | ||
| protein amino acid phosphorylation | P | IEA | IEA | |
| lung development | P | IMP | ISS | |
| extracellular matrix organization and biogenesis | P | IMP | ISS | |
| transmembrane receptor protein tyrosine kinase signaling pathway | P | IEA | IEA | |
| male genitalia development | P | IMP | ISS | |
| anatomical structure morphogenesis | P | IMP | ISS | |
| cell surface receptor linked signal transduction | P | ISS | ||
| odontogenesis (sensu Vertebrata) | P | IMP | ISS | |
| organ morphogenesis | P | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| cellular phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un Un Un Un | ||
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un | ||
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un Un | ||
| lethality-postnatal | MP | Un Un | ||
| muscle phenotype | MP | Un | ||
| skeleton phenotype | MP | Un Un Un Un | ||
| nervous system phenotype | MP | Un Un Un Un | ||
| respiratory system phenotype | MP | Un Un | ||
| limbs/digits/tail phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| digestive/alimentary phenotype | MP | Un Un Un Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| no phenotypic analysis | MP | Un | ||
| growth/size phenotype | MP | Un Un | ||
| pigmentation phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Eosinophilia | D | ISS | ||
| Hypereosinophilic Syndrome | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |