IpiRecord: IPI00203268

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C			ISS IDA
nuclear membrane	C			IDA
membrane	C		IEA
integral to membrane	C		RCA	ISS IEA
integral to plasma membrane	C			ISS
extracellular space	C		RCA	ISS
membrane fraction	C			IDA
rhodopsin-like receptor activity	F		IEA	IEA
receptor activity	F		IEA	TAS IEA
protein binding	F		IPI	ISS
endothelin receptor activity	F		IMP RCA	ISS ISS
type 1 angiotensin receptor binding	F			IPI
G-protein coupled receptor activity	F		IEA	TAS
signal transducer activity	F		IEA
neuropeptide Y receptor activity	F		RCA	ISS
endothelin-B receptor activity	F		IDA	TAS IDA ISS
regulation of epithelial cell proliferation	P			IMP
melanocyte differentiation	P		IDA IMP	IDA ISS
negative regulation of adenylate cyclase activity	P			ISS
nervous system development	P			ISS
blood pressure regulation	P		IMP	ISS IMP
negative regulation of apoptosis	P			IGI
vasoconstriction	P			IMP
regulation of sensory perception of pain	P			IMP
posterior midgut development	P		IMP	ISS
positive regulation of protein amino acid phosphorylation	P			IDA
pigmentation during development	P		IMP	ISS
neural crest cell migration	P		IMP	ISS
pigmentation	P		IMP
regulation of pH	P		IMP	ISS
elevation of cytosolic calcium ion concentration	P			IDA
signal transduction	P		IEA	IEA
enteric nervous system development	P			IGI
vasodilation	P			IMP
regulation of fever	P			IMP
peripheral nervous system development	P		IMP	ISS
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P			ISS IMP
G-protein coupled receptor protein signaling pathway	P		IDA IGI	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (26)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
skin/coat/nails phenotype	MP		Un Un Un Un Un Un
life span-post-weaning/aging	MP		Un Un Un
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un Un
immune system phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
growth/size phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un Un Un Un
lethality-postnatal	MP		Un Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un Un Un
vision/eye phenotype	MP		Un Un
cardiovascular system phenotype	MP		Un Un Un
touch/vibrissae phenotype	MP		Un
pigmentation phenotype	MP		Un Un Un Un Un Un
abnormal enteric ganglia morphology	N			IAGPIAGP
decreased blood pressure	N			IED
increased blood pressure	N			IED
abnormal coat color	N			IAGP
kidney cysts	N			IMP
renal interstitial fibrosis	N			IMP
increased body temperature	N			IED
salt-sensitive hypertension	N			IED
aganglionic megacolon	N			IAGP

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Abnormalities, Multiple	D			ISS
Hypertension, Pulmonary	D			IED
Waardenburg's Syndrome	D			ISS
Myocardial Infarction	D			IED
Myocardial Ischemia	D			ISS
Hirschsprung Disease	D			IAGPISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
calcium/calmodulin dependent kinases pathway	W			IMP

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway