| IPI00205182 - Il6ra, INTERLEUKIN-6 RECEPTOR ALPHA CHAIN PRECURSOR. | |
|---|---|
| Uniprot Accession: P22273 | |
| Uniprot ID: IL6RA_RAT | |
| Mapping: Chr 2, 182078051 - 182128147 | |
| Entrez Gene: 24499 | |
| Entrez MapView: |
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| RGD: 2902 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2574) |
|---|
| Rat: Il6ra, INTERLEUKIN-6 RECEPTOR ALPHA CHAIN PRECURSOR. |
| Mouse: Il6ra, INTERLEUKIN-6 RECEPTOR ALPHA CHAIN PRECURSOR. |
| Rat: Il6ra, INTERLEUKIN 6 RECEPTOR, ALPHA. |
| Human: IL6R, ISOFORM 1 OF INTERLEUKIN-6 RECEPTOR ALPHA CHAIN PRECURSOR. |
| Human: IL6R, ISOFORM 2 OF INTERLEUKIN-6 RECEPTOR ALPHA CHAIN PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | IEA | ||
| membrane | C | IEA IEA | IEA | |
| extracellular space | C | IDA | ||
| integral to membrane | C | RCA | ISS IEA | |
| interleukin-6 receptor complex | C | ISS | ||
| extracellular region | C | ISS | ||
| interleukin receptor activity | F | IEA | ||
| hematopoietin/interferon-class (D200-domain) cytokine receptor activity | F | IEA | IEA | |
| enzyme binding | F | ISS | ||
| receptor activity | F | IEA | IEA | |
| interleukin-6 receptor activity | F | ISS IMP | ||
| cell surface receptor linked signal transduction | P | IEA | ISS | |
| response to lipopolysaccharide | P | IEP | ||
| response to gamma radiation | P | IEP | ||
| response to cAMP | P | IEP | ||
| cell proliferation | P | ISS | ||
| immune response | P | ISS | ||
| response to ethanol | P | IEP | ||
| response to peptide hormone stimulus | P | IEP | ||
| response to glucocorticoid stimulus | P | IEP | ||
| multicellular organismal development | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Acute-Phase Reaction | D | IEP | ||
| Obesity | D | ISSISSISS | ||
| Seizures | D | IEP | ||
| Metabolic Syndrome X | D | ISS | ||
| Myocardial Infarction | D | IEP | ||
| Insulin Resistance | D | ISS | ||
| Orchitis | D | IEP | ||
| Myocardial Reperfusion Injury | D | ISS | ||
| Heart Failure, Congestive | D | IEP | ||
| Hypertension | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hematopoietic cell lineage (04640) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |