IpiRecord: IPI00206056

IPI00206056 - Tnfrsf6, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 PRECURSOR.
Uniprot Accession: Q63199
Uniprot ID: TNR6_RAT
Mapping: Chr 1, 238259337 - 238274745
Entrez Gene: 246097
Entrez MapView: Geneprod
RGD: 619831
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1824)
Rat: Tnfrsf6, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 PRECURSOR.
Mouse: Fas, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 PRECURSOR.
Rat: Tnfrsf6, FAS RECEPTOR (FRAGMENT).
Rat: Tnfrsf6, 36 KDA PROTEIN.
Human: FAS, PRECURSOR.
Human: FAS, PRECURSOR.
Human: FAS, PRECURSOR.
Human: FAS, PRECURSOR.
Human: FAS, (FRAGMENT).
Human: FAS, PRECURSOR.
Human: FAS, PRECURSOR.
Human: FAS, PRECURSOR.
Human: FAS, 38 KDA PROTEIN.

Annotations for Tnfrsf6 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
external side of plasma membraneCIDA IDA ISS IEA 
caveolaCIEP 
membraneCIEA IEA IEA IEA 
integral to membraneCRCA ISS IEA 
tumor necrosis factor receptor activityFTAS 
receptor activityFIEA IEA TAS 
protein bindingFIEA IPI IPI IEA 
transmembrane receptor activityFIEA IEA NAS IEA 
menstrual cyclePIEP 
transformed cell apoptosisPIDA ISS IEA 
positive regulation of apoptosisPIGI 
response to peptide hormone stimulusPIEP 
negative thymic T cell selectionPIMP ISS IEA 
response to hypoxiaPIEP 
immune responsePIEA IEA IEA 
induction of apoptosis via death domain receptorsPIMP IDA IGI IMP ISS IEA 
apoptosisPIEA IGI ISS TAS ISS IEA 
response to estrogen stimulusPIEP 
inflammatory cell apoptosisPIDA IMP ISS IEA 
activated T cell apoptosisPIDA ISS IEA 
induction of apoptosisPIEP 
signal transductionPIEA IEA IEA 
induction of apoptosis by extracellular signalsPIMP 
response to drugPIEP 
agingPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (20)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMP#
skin/coat/nails phenotypeMP#
behavior/neurological phenotypeMP#
endocrine/exocrine gland phenotypeMP#
homeostasis/metabolism phenotypeMP#
immune system phenotypeMP######
renal/urinary system phenotypeMP##
nervous system phenotypeMP#
respiratory system phenotypeMP#
tumorigenesisMP#
cardiovascular system phenotypeMP#
digestive/alimentary phenotypeMP#
reproductive system phenotypeMP#
hearing/vestibular/ear phenotypeMP#
hematopoietic system phenotypeMP#####
no phenotypic analysisMP#
growth/size phenotypeMP##
liver/biliary system phenotypeMP###
pigmentation phenotypeMP#
life span-post-weaning/agingMP####

Disease (12)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Lymphoproliferative DisordersDISS
Brain InjuriesDIEP
Ocular HypertensionDIEP
Retinal DetachmentDIEP
AsthmaDIEP
NephrosisDIEP
Cardiomyopathy, CongestiveDIEP
Brain IschemiaDIEP
Colonic NeoplasmsDIEP
Brain Diseases, MetabolicDIEP
Reperfusion InjuryDIEP
VaricoceleDIEP

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
intrinsic apoptotic pathwayWIEP
extrinsic death receptor pathwayWIEP

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway