IpiRecord: IPI00206172

IPI00206172 - Mapk3, ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 3.
Uniprot Accession: P21708-1
Uniprot ID: MK03_RAT
Mapping: Chr 1, 185935044 - 185941249
Entrez Gene: 50689
Entrez MapView: Geneprod
RGD: 3046
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1254)
Rat: Mapk3, ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 3.
Mouse: Mapk3, MITOGEN-ACTIVATED PROTEIN KINASE 3.
Mouse: Mapk3, FULL INSERT SEQUENCE.
Mouse: Mapk3, 42 KDA PROTEIN.
Rat: Mapk3, ISOFORM 2 OF MITOGEN-ACTIVATED PROTEIN KINASE 3.
Rat: Mapk3, 42 KDA PROTEIN.
Human: MAPK3, MITOGEN-ACTIVATED PROTEIN KINASE 3.
Human: MAPK3, EXTRACELLULAR SIGNAL-RELATED KINASE 1C.
Human: MAPK3, MITOGEN-ACTIVATED PROTEIN KINASE 3 ISOFORM 2.
Human: MAPK3, PUTATIVE UNCHARACTERIZED PROTEIN.

Annotations for Mapk3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
cytoplasmCIDA IDA ISS 
nucleusCIDA ISS 
cytosolCIDA 
insoluble fractionCIDA 
protein bindingFIPI IPI IPI IPI IPI IPI ISS ISS 
MAP kinase activityFNAS IEA TAS IMP IPI TAS ISS ISS 
kinase activityFIEA 
protein serine/threonine kinase activityFIEA IEA IEA 
protein-tyrosine kinase activityFISS 
ATP bindingFNAS IEA IEA IEA ISS 
nucleotide bindingFIEA IEA 
phosphotyrosine bindingFIMP ISS 
transferase activityFIEA IEA 
protein kinase activityFIEA IDA ISS 
positive regulation of transcriptionPIEP 
response to lipopolysaccharidePIDA 
lipopolysaccharide-mediated signaling pathwayPIDA 
regulation of progression through cell cyclePNAS ISS 
protein amino acid phosphorylationPIDA IEA IDA IDA TAS ISS ISS 
intracellular signaling cascadePIDA 
cell cyclePIEA IEA 
protein kinase cascadePTAS 
response to exogenous dsRNAPIDA 
sensory perception of painPIMP 
phosphorylationPTAS ISS 
signal transductionPTAS ISS 
nuclear translocation of MAPKPIDA 
organ morphogenesisPIDA ISS 
response to DNA damage stimulusPIDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn Un
immune system phenotypeMPUn Un
nervous system phenotypeMPUn Un
hematopoietic system phenotypeMPUn
decreased thymocyte numberNISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
The extracellular signal-regulated RAF/MEK/ERK pathwayWIDAIMP

KEGG Pathway (22)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
TGF-beta signaling pathway (04350)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Dorso-ventral axis formation (04320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway