| IPI00206172 - Mapk3, ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 3. | |
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| Uniprot Accession: P21708-1 | |
| Uniprot ID: MK03_RAT | |
| Mapping: Chr 1, 185935044 - 185941249 | |
| Entrez Gene: 50689 | |
| Entrez MapView: |
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| RGD: 3046 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1254) |
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| Rat: Mapk3, ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 3. |
| Mouse: Mapk3, MITOGEN-ACTIVATED PROTEIN KINASE 3. |
| Mouse: Mapk3, FULL INSERT SEQUENCE. |
| Mouse: Mapk3, 42 KDA PROTEIN. |
| Rat: Mapk3, ISOFORM 2 OF MITOGEN-ACTIVATED PROTEIN KINASE 3. |
| Rat: Mapk3, 42 KDA PROTEIN. |
| Human: MAPK3, MITOGEN-ACTIVATED PROTEIN KINASE 3. |
| Human: MAPK3, EXTRACELLULAR SIGNAL-RELATED KINASE 1C. |
| Human: MAPK3, MITOGEN-ACTIVATED PROTEIN KINASE 3 ISOFORM 2. |
| Human: MAPK3, PUTATIVE UNCHARACTERIZED PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| cytoplasm | C | IDA IDA | ISS | |
| nucleus | C | IDA | ISS | |
| cytosol | C | IDA | ||
| insoluble fraction | C | IDA | ||
| protein binding | F | IPI IPI IPI | IPI IPI IPI | ISS ISS |
| MAP kinase activity | F | NAS IEA | TAS IMP IPI | TAS ISS ISS |
| kinase activity | F | IEA | ||
| protein serine/threonine kinase activity | F | IEA | IEA IEA | |
| protein-tyrosine kinase activity | F | ISS | ||
| ATP binding | F | NAS IEA | IEA IEA | ISS |
| nucleotide binding | F | IEA | IEA | |
| phosphotyrosine binding | F | IMP | ISS | |
| transferase activity | F | IEA | IEA | |
| protein kinase activity | F | IEA | IDA | ISS |
| positive regulation of transcription | P | IEP | ||
| response to lipopolysaccharide | P | IDA | ||
| lipopolysaccharide-mediated signaling pathway | P | IDA | ||
| regulation of progression through cell cycle | P | NAS | ISS | |
| protein amino acid phosphorylation | P | IDA IEA | IDA IDA | TAS ISS ISS |
| intracellular signaling cascade | P | IDA | ||
| cell cycle | P | IEA | IEA | |
| protein kinase cascade | P | TAS | ||
| response to exogenous dsRNA | P | IDA | ||
| sensory perception of pain | P | IMP | ||
| phosphorylation | P | TAS | ISS | |
| signal transduction | P | TAS | ISS | |
| nuclear translocation of MAPK | P | IDA | ||
| organ morphogenesis | P | IDA | ISS | |
| response to DNA damage stimulus | P | IDA | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un Un | ||
| immune system phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| decreased thymocyte number | N | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| The extracellular signal-regulated RAF/MEK/ERK pathway | W | IDAIMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Dorso-ventral axis formation (04320) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term potentiation (04720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |