IpiRecord: IPI00206406

IPI00206406 - Ppp3r1, ISOFORM 1 OF CALCINEURIN SUBUNIT B ISOFORM 1.
Uniprot Accession: P63100-1
Uniprot ID: CANB1_RAT
Mapping: Chr 14, 98047333 - 98131590
Entrez Gene: 29748
Entrez MapView: Geneprod
RGD: 69230
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12101)
Rat: Ppp3r1, ISOFORM 1 OF CALCINEURIN SUBUNIT B ISOFORM 1.
Mouse: Wdr92, ISOFORM 1 OF CALCINEURIN SUBUNIT B ISOFORM 1.
Mouse: Ppp3r1, ISOFORM 2 OF CALCINEURIN SUBUNIT B ISOFORM 1.
Mouse: Ppp3r1, HZGJ-LIKE PROTEIN.
Rat: Ppp3r1, ISOFORM 2 OF CALCINEURIN SUBUNIT B ISOFORM 1.
Rat: Ppp3r1, 32 KDA PROTEIN.
Human: PPP3R1, CALCINEURIN SUBUNIT B ISOFORM 1.
Human: WDR92, CDNA FLJ25361 FIS, CLONE TST01713.
Human: WDR92, HZGJ.
Human: WDR92, 18 KDA PROTEIN.
Human: WDR92, WD REPEAT-CONTAINING PROTEIN 92.

Annotations for Ppp3r1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
calcineurin complexCNAS ISS 
cytoplasmCIEA 
calcium-dependent protein serine/threonine phosphatase activityFNAS 
ATP bindingFIEA 
protein heterodimerization activityFISS 
protein bindingFIPI IPI 
calcium ion bindingFNAS IEA IEA ISS 
phosphoprotein phosphatase activityFIDA 
calmodulin inhibitor activityFNAS 
aminoacyl-tRNA ligase activityFIEA 
nucleotide bindingFIEA 
epithelial to mesenchymal transitionPIMP ISS 
tRNA aminoacylation for protein translationPIEA 
protein amino acid dephosphorylationPIDA 
apoptosisPIEA IEA 
heart developmentPIMP ISS 
translationPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn
life span-post-weaning/agingMPUn
growth/size phenotypeMPUn Un Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertrophy, Left VentricularDISSISS
Cardiomyopathy, CongestiveDISS
Myocardial IschemiaDIED

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
calcineurin signaling pathwayWISS
mitogen activated protein kinase signaling pathwayWIEA

KEGG Pathway (10)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway