IpiRecord: IPI00206535

IPI00206535 - Il12a, INTERLEUKIN-12 SUBUNIT ALPHA PRECURSOR.
Uniprot Accession: Q9R103
Uniprot ID: IL12A_RAT
Mapping: Chr 2, 158710261 - 158717689
Entrez Gene: 84405
Entrez MapView: Geneprod
RGD: 620562
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2417)
Rat: Il12a, INTERLEUKIN-12 SUBUNIT ALPHA PRECURSOR.
Mouse: Il12a, INTERLEUKIN-12 SUBUNIT ALPHA PRECURSOR.
Mouse: Il12a, INTERLEUKIN 12A.
Human: IL12A, INTERLEUKIN 12A PRECURSOR.
Human: IL12A, INTERLEUKIN-12 P35 SUBUNIT.

Annotations for Il12a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS IEA 
integral to membraneCISS 
extracellular regionCIEA IEA IEA 
interleukin-12 complexCNAS 
interleukin-12 receptor bindingFTAS IEA IEA IEA 
interleukin-12 beta subunit bindingFIEA IPI ISS IEA 
protein bindingFIPI IEA 
growth factor activityFIEA IEA 
cytokine activityFTAS IDA IDA IEA 
interleukin-27 bindingFIPI IEA 
positive regulation of T cell proliferationPIEA IDA IEA 
immune responsePTAS IEA IEA ISS IEA 
positive regulation of tyrosine phosphorylation of Stat4 proteinPIDA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
tumorigenesisMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway