IpiRecord: IPI00206669

IPI00206669 - Il3, INTERLEUKIN-3 BETA.
Uniprot Accession: P97688
Uniprot ID: P97688_RAT
Mapping: Chr 10, 39684691 - 39687041
Entrez Gene: 24495
Entrez MapView: Geneprod
RGD: 2897
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9363)
Rat: Il3, INTERLEUKIN-3 BETA.
Mouse: Il3, INTERLEUKIN-3 PRECURSOR.
Human: IL3, INTERLEUKIN-3 PRECURSOR.

Annotations for Il3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCISS RCA ISS IEA 
extracellular regionCIEA IEA IEA 
interleukin-3 receptor bindingFTAS IEA IMP ISS IEA 
cytokine activityFIEA IDA IDA IDA IDA IDA IDA ISS IEA 
growth factor activityFIEA IEA 
positive regulation of protein amino acid phosphorylationPIDA 
cytokine and chemokine mediated signaling pathwayPIEA IDA 
negative regulation of apoptosisPIEA IDA 
nervous system developmentPTAS ISS 
regulation of cell growthPIMP 
immune responsePIEA IEA IEA 
positive regulation of peptidyl-tyrosine phosphorylationPISS IDA IDA ISS 
positive regulation of cell proliferationPISS IDA IDA IMP ISS 
positive regulation of survival gene product activityPISS IDA IDA ISS 
hemopoiesisPIMP 
cell-cell signalingPTAS ISS 
positive regulation of JNK cascadePIEA IDA IMP 
response to hormone stimulusPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMP##
lethality-postnatalMP#
renal/urinary system phenotypeMP#
respiratory system phenotypeMP##
tumorigenesisMP#
hematopoietic system phenotypeMP##
life span-post-weaning/agingMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway