IpiRecord: IPI00207182

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
membrane	C	IEA	IEA
cytoplasm	C		TAS	ISS
lipid raft	C		IDA
cytoskeleton	C	IEA	IEA	IEA
nucleotide binding	F	IEA	IEA	IEA
receptor binding	F	IPI		ISS
non-membrane spanning protein tyrosine kinase activity	F	IEA
protein-tyrosine kinase activity	F	IEA	IDA	ISS ISS IEA
protein binding	F		IPI IPI IPI IPI	ISS
ATP binding	F	IEA	IEA IEA	IEA
protein serine/threonine kinase activity	F			ISS
protein kinase activity	F		IEA
kinase activity	F		IEA
growth hormone receptor binding	F			IPI
SH2 domain binding	F	IPI		ISS
transferase activity	F	IEA	IEA	IEA
Janus kinase activity	F	IEA	IDA IMP	ISS IEA
cell motility	P	TAS		ISS
regulation of progression through cell cycle	P	TAS		ISS
cell differentiation	P		IMP	ISS
negative regulation of cell proliferation	P	IEA	IMP	ISS
apoptosis	P	IEA	IDA IMP	ISS
protein amino acid phosphorylation	P	IEA	IEA	ISS IEA
intracellular signaling cascade	P	TAS	IEA	ISS IEA
STAT protein nuclear translocation	P	IEA	IDA	ISS
peptidyl-tyrosine phosphorylation	P		IDA	ISS
cytokine and chemokine mediated signaling pathway	P		TAS	ISS
tyrosine phosphorylation of STAT protein	P	IEA	IMP	ISS
protein kinase cascade	P		IDA
myeloid cell differentiation	P	IEA	IMP	ISS
JAK-STAT cascade	P		IMP IDA IMP	ISS ISS IDA
enzyme linked receptor protein signaling pathway	P		IDA
mesoderm development	P	TAS		ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
growth/size phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un Un Un
hematopoietic system phenotype	MP		Un Un Un Un
normal phenotype	MP		Un
reproductive system phenotype	MP		Un
embryonic lethality	N			ISS
abnormal erythropoiesis	N			ISS

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Obesity	D			ISS
Thrombocytosis	D			ISS
Myelofibrosis	D			ISS
Polycythemia Vera	D			ISS

Pathway (8)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
somatostatin signaling pathway	W			IMP
leptin system pathway	W			ISS
Angiotensin II signaling pathway	W			IMP
growth hormone signaling pathway	W			IDA
platelet-derived growth factor signaling pathway	W			IMP
aldosterone signaling pathway	W			IMP
altered JAK-STAT signaling pathway	W			ISS
JAK-STAT signaling pathway	W			IDAIEA IDAISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway