| IPI00208472 - Thbd, THROMBOMODULIN. | |
|---|---|
| Uniprot Accession: Q792T4 | |
| Uniprot ID: Q792T4_RAT | |
| Mapping: Chr 3, 137160721 - 137162454 | |
| Entrez Gene: 83580 | |
| Entrez MapView: |
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| RGD: 621299 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4001) |
|---|
| Rat: Thbd, THROMBOMODULIN. |
| Mouse: Thbd, THROMBOMODULIN PRECURSOR. |
| Human: THBD, THROMBOMODULIN PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | TAS | ||
| integral to membrane | C | RCA | ISS | |
| extracellular space | C | RCA | ISS IDA | |
| membrane | C | IEA | IEA IEA | |
| cell surface | C | TAS | ||
| plasma membrane | C | TAS | IDA ISS | |
| calcium ion binding | F | TAS | IEA | IEA |
| transmembrane receptor activity | F | IEA | IEA | IEA |
| protein domain specific binding | F | ISS | ||
| protease binding | F | ISS | ||
| protein binding | F | IPI | ||
| receptor activity | F | IEA | ||
| molecular_function | F | ND | ||
| sugar binding | F | IEA | IEA | IEA |
| response to cAMP | P | IEP | ||
| response to lipopolysaccharide | P | IEP | ||
| embryonic development | P | IEA | IMP | ISS |
| female pregnancy | P | IEA | IMP | ISS |
| response to X-ray | P | IEP | ||
| blood coagulation | P | TAS | TAS | IDA ISS IEA |
| negative regulation of coagulation | P | TAS | ISS ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| normal phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiovascular Diseases | D | TAS | ||
| Obesity | D | ISS | ||
| Hypertension, Pulmonary | D | ISS | ||
| Vascular Diseases | D | TAS | ||
| Metabolic Syndrome X | D | ISS | ||
| Liver Failure, Acute | D | IEP | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Autoimmune Diseases | D | TAS | ||
| Respiratory Distress Syndrome, Adult | D | IEP | ||
| Coronary Arteriosclerosis | D | ISS | ||
| Hyperlipidemia, Familial Combined | D | ISS | ||
| Endotoxemia | D | IEP | ||
| Hypertension | D | ISSIEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| protein C anticoagulant pathway | W | TAS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |