| IPI00208672 - Crk, ISOFORM CRK-I OF PROTO-ONCOGENE C-CRK. | |
|---|---|
| Uniprot Accession: Q63768-2 | |
| Uniprot ID: CRK_RAT | |
| Mapping: Chr 10, 63017662 - 63040420 | |
| Entrez Gene: 54245 | |
| Entrez MapView: |
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| RGD: 2405 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9537) |
|---|
| Rat: Crk, ISOFORM CRK-I OF PROTO-ONCOGENE C-CRK. |
| Mouse: Crk, ISOFORM CRK-II OF PROTO-ONCOGENE C-CRK. |
| Mouse: Crk, ISOFORM CRK-I OF PROTO-ONCOGENE C-CRK. |
| Mouse: Crk, CT-10 RELATED KINASE 3. |
| Mouse: Crk, SEQUENCE. |
| Mouse: Crk, V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG. |
| Mouse: Crk, CRK PROTEIN. |
| Rat: Crk, ISOFORM CRK-II OF PROTO-ONCOGENE C-CRK. |
| Rat: Crk, 29 KDA PROTEIN. |
| Human: CRK, ISOFORM CRK-II OF PROTO-ONCOGENE C-CRK. |
| Human: CRK, V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG ISOFORM B. |
| Human: CRK, ISOFORM CRK-I OF PROTO-ONCOGENE C-CRK. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | ISS | ||
| cytoplasm | C | IEA | ISS | |
| intracellular | C | IEA | ||
| membrane | C | IEA | ||
| protein binding, bridging | F | IMP | ||
| protein binding | F | IPI IPI IPI IPI | ISS ISS | |
| kinase activity | F | IEA | ||
| protein phosphorylated amino acid binding | F | IDA | ISS | |
| protein domain specific binding | F | IPI | ||
| SH2 domain binding | F | ISS | ||
| SH3/SH2 adaptor activity | F | ISS | ||
| actin cytoskeleton organization and biogenesis | P | ISS | ||
| activation of JNK activity | P | TAS | ||
| regulation of progression through cell cycle | P | IEA | ||
| intracellular signaling cascade | P | IEA | IEA | |
| cellular process | P | IEA | ||
| regulation of cell motility | P | TAS | ||
| regulation of Rac protein signal transduction | P | IMP | ||
| regulation of transcription from RNA polymerase II promoter | P | ISS | ||
| cell motility | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| muscle phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| normal phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |