IpiRecord: IPI00208989

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
phosphoinositide 3-kinase complex	C	IEA	IEA	IEA
cellular_component	C		ND
brush border membrane	C			IDA
kinase activity	F		IEA
1-phosphatidylinositol-3-kinase activity	F	TAS	IMP IMP	IDA ISS ISS IEA
phosphotransferase activity, alcohol group as acceptor	F		IEA
transferase activity	F	IEA	IEA	IEA
inositol or phosphatidylinositol kinase activity	F	IEA	IEA	IEA
insulin receptor substrate binding	F	IEA	IPI	ISS IEA
phosphatidylinositol-4,5-bisphosphate 3-kinase activity	F	IEA	IEA	IEA
phosphoinositide 3-kinase activity	F			NAS
activation of MAPK activity	P	TAS		ISS
regulation of progression through cell cycle	P	TAS		ISS
phosphoinositide-mediated signaling	P	IEA	IEA
platelet activation	P	IEA	IMP	ISS IEA
G-protein coupled receptor protein signaling pathway	P	TAS		ISS
homophilic cell adhesion	P	IEA	IMP	ISS IEA
cellular calcium ion homeostasis	P	IEA	IMP	ISS IEA
embryonic cleavage	P	IEA	IMP	ISS IEA
chemotaxis	P	TAS		ISS
signal transduction	P	NAS	IEA	ISS IEA
phosphoinositide phosphorylation	P	IEA	IEA
regulation of cell-matrix adhesion	P	IEA	IMP	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
immune system phenotype	MP		Un
lethality-postnatal	MP		Un
cardiovascular system phenotype	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Thrombosis	D			ISS

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
inositol phosphate metabolic pathway	W			IEA
programmed cell death pathway	W			IEA
phosphatidylinositol 3 kinase-Akt signaling pathway	W			IEA
JAK-STAT signaling pathway	W			IEA

KEGG Pathway (20)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
B cell receptor signaling pathway (04662)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
mTOR signaling pathway (04150)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Leukocyte transendothelial migration (04670)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Inositol phosphate metabolism (00562)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Phosphatidylinositol signaling system (04070)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway