| IPI00209445 - Htr2a, 5-HYDROXYTRYPTAMINE RECEPTOR 2A. | |
|---|---|
| Uniprot Accession: P14842 | |
| Uniprot ID: 5HT2A_RAT | |
| Mapping: Chr 15, 55463338 - 55533964 | |
| Entrez Gene: 29595 | |
| Entrez MapView: |
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| RGD: 61800 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12508) |
|---|
| Rat: Htr2a, 5-HYDROXYTRYPTAMINE RECEPTOR 2A. |
| Mouse: Htr2a, 5-HYDROXYTRYPTAMINE RECEPTOR 2A. |
| Human: HTR2A, 5-HYDROXYTRYPTAMINE RECEPTOR 2A. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| dendrite | C | IDA | ||
| cytoplasm | C | IDA | ||
| integral to plasma membrane | C | TAS | ISS | |
| integral to membrane | C | RCA | ISS IEA | |
| membrane | C | IEA | IEA | IEA |
| receptor activity | F | IEA | IEA | IEA |
| G-protein coupled receptor activity | F | IEA | ||
| rhodopsin-like receptor activity | F | IEA | IEA | IEA |
| protein complex binding | F | IPI | ||
| signal transducer activity | F | IEA | ||
| serotonin receptor activity | F | TAS | RCA | ISS ISS |
| positive regulation of MAPK activity | P | IMP | ||
| regulation of dopamine secretion | P | IMP | ||
| cell death | P | IMP | ||
| serotonin receptor signaling pathway | P | TAS | ISS | |
| serotonin receptor, phospholipase C activating pathway | P | IDA | ||
| synaptic transmission | P | TAS | ISS | |
| G-protein coupled receptor protein signaling pathway | P | IEA IEA | IEA | |
| negative regulation of synaptic transmission, glutamatergic | P | IMP | ||
| thermoregulation | P | IMP | ||
| positive regulation of vasoconstriction | P | IMP | ||
| memory | P | IMP | ||
| positive regulation of cell proliferation | P | IMP | ||
| response to stress | P | IMP | ||
| sleep | P | IMP | ||
| negative regulation of potassium ion transport | P | IMP | ||
| signal transduction | P | IEA | IEA | IEA |
| sensory perception of pain | P | IMP | ||
| response to drug | P | IMP | ||
| aging | P | IEP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Pancreatitis | D | IED | ||
| Obesity | D | ISSISS | ||
| Anoxia | D | IEP | ||
| Insulin Resistance | D | ISS | ||
| Hyperphagia | D | IED | ||
| Back Pain | D | IED | ||
| Heart Failure, Congestive | D | IED | ||
| Hyperglycemia | D | IED | ||
| Hypertension | D | ISSISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Neuroactive ligand-receptor interaction (04080) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |