| IPI00210078 - Chek1, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE CHK1. | |
|---|---|
| Uniprot Accession: Q91ZN7-1 | |
| Uniprot ID: CHK1_RAT | |
| Mapping: Chr 8, 37954322 - 37974748 | |
| Entrez Gene: 140583 | |
| Entrez MapView: |
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| RGD: 620545 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7773) |
|---|
| Rat: Chek1, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE CHK1. |
| Mouse: Chek1, ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE CHK1. |
| Mouse: Chek1, ISOFORM 1 OF SERINE/THREONINE-PROTEIN KINASE CHK1. |
| Rat: Chek1, ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE CHK1. |
| Human: CHEK1, SERINE/THREONINE-PROTEIN KINASE CHK1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IEA | IDA | ISS |
| cytoplasm | C | IEA | IEA | |
| condensed nuclear chromosome | C | TAS | ISS | |
| replication fork | C | IEA | IDA | ISS |
| protein kinase activity | F | IMP | ISS ISS | |
| protein-tyrosine kinase activity | F | ISS | ||
| protein serine/threonine kinase activity | F | IEA | IEA IEA | |
| kinase activity | F | IEA | ||
| ATP binding | F | IEA | IEA IEA | |
| protein binding | F | IPI IPI IPI IPI | IPI | ISS |
| nucleotide binding | F | IEA | IEA | |
| transferase activity | F | IEA | IEA | |
| negative regulation of cell proliferation | P | TAS | ISS | |
| cell cycle checkpoint | P | ISS | ||
| protein amino acid phosphorylation | P | IEA | IDA | ISS ISS |
| cell cycle | P | IEA | IEA | |
| DNA repair | P | IEA | IDA | ISS |
| gamete generation | P | TAS | ISS | |
| regulation of cyclin-dependent protein kinase activity | P | TAS | ISS | |
| DNA damage checkpoint | P | TAS | IDA IMP | ISS ISS |
| meiotic recombination | P | TAS | ISS | |
| response to DNA damage stimulus | P | IDA IDA | ISS | |
| G2/M transition of mitotic cell cycle | P | IEA | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| tumorigenesis | MP | Un | ||
| reproductive system phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |