IpiRecord: IPI00210294

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C			IDA
membrane	C	IEA	IEA IEA	IEA
integral to plasma membrane	C	NAS	TAS	ISS ISS
extracellular space	C		RCA	IDA ISS
integral to membrane	C		RCA IEA	ISS IEA
protein binding	F		IPI	ISS
receptor activity	F		IEA	IEA
hematopoietin/interferon-class (D200-domain) cytokine receptor activity	F		IEA
molecular_function	F	ND
protein-hormone receptor activity	F			IDA IMP
peptide hormone binding	F			IMP IDA
transmembrane receptor activity	F		TAS	ISS
regulation of metabolic process	P		TAS	ISS
female pregnancy	P			IEP
negative regulation of hydrolase activity	P		IGI
cholesterol metabolic process	P		IGI
cell surface receptor linked signal transduction	P			ISS
generation of precursor metabolites and energy	P			NAS
response to chemical stimulus	P			IEP
response to nicotine	P			IEP
energy reserve metabolic process	P			ISS
cellular response to nutrient levels	P			IEP
eating behavior	P			IMP
ovulation from ovarian follicle	P			IEP
signal transduction	P		TAS	ISS
angiogenesis	P			IMP
biological_process	P	ND
multicellular organismal development	P			ISS
response to estrogen stimulus	P			IEP

Cellular Component

Biological Process

Molecular Function

Phenotype (17)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
adipose tissue phenotype	MP		Un Un Un Un Un
behavior/neurological phenotype	MP		Un Un Un Un Un
endocrine/exocrine gland phenotype	MP		Un Un Un Un Un
homeostasis/metabolism phenotype	MP		Un Un Un Un Un Un Un Un
immune system phenotype	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un
normal phenotype	MP		Un Un
cardiovascular system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un Un Un
hematopoietic system phenotype	MP		Un Un
reproductive system phenotype	MP		Un Un Un Un
liver/biliary system phenotype	MP		Un
life span-post-weaning/aging	MP		Un Un Un
growth/size phenotype	MP		Un Un Un Un Un Un Un Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Obesity	D			ISSIAGP
Arteriosclerosis	D			ISS

Pathway (5)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
obesity disease pathway	W			ISS
altered leptin system pathway	W			TASISS
leptin system pathway	W			TASISSISS
energy homeostasis pathway	W			TAS
altered energy homeostasis pathway	W			TAS

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway