IpiRecord: IPI00210301

IPI00210301 - Cd40lg, CD40 LIGAND.
Uniprot Accession: A0SZW2
Uniprot ID: A0SZW2_RAT
Mapping: Chr X, 141925019 - 141937183
Entrez Gene: 84349
Entrez MapView: Geneprod
RGD: 708418
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_15021)
Rat: Cd40lg, CD40 LIGAND.
Mouse: Cd40lg, CD40 LIGAND.
Human: CD40LG, CD40 LIGAND.
Human: CD40LG, CD154 PROTEIN.

Annotations for Cd40lg and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS 
plasma membraneCIEA 
integral to membraneCIEA RCA ISS IEA 
extracellular spaceCIEA IEA IEA 
soluble fractionCTAS 
cellular_componentCND 
membraneCIEA IEA IEA IEA 
CD40 receptor bindingFIPI ISS ISS 
cytokine activityFIEA IEA IEA 
molecular_functionFND 
tumor necrosis factor receptor bindingFIEA IEA IEA 
B cell differentiationPIGI IEA 
regulation of immunoglobulin secretionPIDA ISS IEA 
isotype switchingPISS IDA IEA 
platelet activationPIDA ISS 
leukocyte adhesionPNAS 
immunoglobulin secretionPIGI ISS 
defense responsePIEA 
inflammatory responsePIDA ISS 
immune responsePIEA IEA IEA 
B cell proliferationPIDA ISS 
signal transductionPNAS ISS 
anti-apoptosisPIDA 
biological_processPND 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
other phenotypeMPUn
immune system phenotypeMPUn Un
skeleton phenotypeMPUn
nervous system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn
reproductive system phenotypeMPUn
hematopoietic system phenotypeMPUn Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
DysgammaglobulinemiaDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway