IpiRecord: IPI00210692

IPI00210692 - Casp7, CASPASE-7.
Uniprot Accession: O88550
Uniprot ID: O88550_RAT
Mapping: Chr 1, 262689300 - 262721591
Entrez Gene: 64026
Entrez MapView: Geneprod
RGD: 620944
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1968)
Rat: Casp7, CASPASE-7.
Mouse: Casp7, CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM BETA OF CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM ALPHA' OF CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM ALPHA OF CASPASE-7 PRECURSOR.
Human: CASP7, UNCHARACTERIZED PROTEIN CASP7.
Human: CASP7, CASPASE 7, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.

Annotations for Casp7 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
endoplasmic reticulum membraneCISS 
cytoplasmCIEA ISS 
mitochondrial membraneCISS 
protein bindingFISS 
peptidase activityFIEA 
hydrolase activityFIEA 
cysteine-type peptidase activityFIEA IEA ISS IEA 
caspase activityFIEA RCA IDA ISS ISS IEA IDA 
response to UVPIGI ISS 
apoptosisPIEA IEA TAS 
regulation of apoptosisPRCA ISS 
induction of apoptosisPIGI RCA IEA ISS 
heart developmentPIGI ISS 
apoptotic programPISS 
proteolysisPIEA RCA ISS ISS IEA IDA 
release of cytochrome c from mitochondriaPIGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
lethality-embryonic/perinatalMP#
vision/eye phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Dentatorubropallidoluysian atrophy (DRPLA) (05050)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Neurodegenerative Disorders (01510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway