IpiRecord: IPI00210825

IPI00210825 - Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2.
Uniprot Accession: Q590M0
Uniprot ID: Q590M0_RAT
Mapping: Chr 6, 21453511 - 21489427
Entrez Gene: 64677
Entrez MapView: Geneprod
RGD: 621480
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6168)
Rat: Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2.
Mouse: Srd5a2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2.
Human: SRD5A2, 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2.

Annotations for Srd5a2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
membraneCIEA RCA ISS IEA 
integral to membraneCIEA RCA ISS IEA 
microsomeCIEA IEA IEA 
endoplasmic reticulumCIEA IEA IEA 
3-oxo-5-alpha-steroid 4-dehydrogenase activityFIEA IMP IMP IDA ISS IEA 
oxidoreductase activityFIEA IEA IEA 
sterol 5-alpha reductase activityFIDA ISS IEA 
male genitalia developmentPIEA IMP TAS ISS IEA 
response to steroid hormone stimulusPIEP 
androgen biosynthetic processPIEA IMP ISS IEA 
response to peptide hormone stimulusPIDA 
response to organic substancePIDA 
cell differentiationPIEA IEA IEA 
cell-cell signalingPTAS ISS 
steroid catabolic processPIDA 
sex determinationPIEA 
sex differentiationPIEA IEA TAS IEA 
androgen metabolic processPISS 
steroid biosynthetic processPIMP IDA ISS 
response to drugPIDA 
male gonad developmentPIMP ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
reproductive system phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Diabetes MellitusDIEP
HypospadiasDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
bile acid biosynthetic pathwayWIEA
androgen and estrogen metabolic pathwayWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Androgen and estrogen metabolism (00150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Bile acid biosynthesis (00120)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway