IpiRecord: IPI00211005

IPI00211005 - Igf1r, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR PRECURSOR.
Uniprot Accession: P24062
Uniprot ID: IGF1R_RAT
Mapping: Chr 1, 122704987 - 122989472
Entrez Gene: 25718
Entrez MapView: Geneprod
RGD: 2869
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17559)
Rat: Igf1r, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR PRECURSOR.
Human: IGF1R, PUTATIVE UNCHARACTERIZED PROTEIN.
Human: IGF1R, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR PRECURSOR.
Human: IGF1R, CONSERVED HYPOTHETICAL PROTEIN.

Annotations for Igf1r and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCISS 
neuron projectionCIDA 
integral to plasma membraneCIC ISS 
membraneCIEA IEA 
integral to membraneCISS IEA 
nucleotide bindingFIEA IEA 
receptor activityFIEA IEA 
insulin-like growth factor bindingFIDA IDA TAS ISS ISS ISS 
transferase activityFIEA IEA 
phosphoinositide 3-kinase bindingFIPI ISS ISS 
insulin-like growth factor receptor activityFIDA TAS ISS ISS 
protein bindingFISS 
ATP bindingFIEA IEA 
protein serine/threonine kinase activityFISS 
insulin receptor substrate bindingFIPI ISS IPI ISS 
axonogenesisPIMP 
regulation of progression through cell cyclePTAS ISS 
protein amino acid autophosphorylationPIDA IDA IDA ISS ISS 
establishment of cell polarityPIMP 
positive regulation of cell proliferationPTAS ISS 
neurite developmentPIDA 
insulin-like growth factor receptor signaling pathwayPIDA ISS ISS ISS 
anti-apoptosisPTAS ISS 
signal transductionPTAS ISS 
insulin receptor signaling pathwayPTAS ISS 
organ morphogenesisPIEA ISS IEA 
protein tetramerizationPIDA ISS ISS 
brain developmentPIEA ISS ISS IEA 
male sex determinationPIEA ISS IEA 
protein heterooligomerizationPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Fetal Growth RetardationDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
insulin-like growth factor signaling pathwayWIMPISS

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway