IpiRecord: IPI00211380
| IPI00211380 - Pik3ca, P110) (PI3K) ISOFORM 1. | |
|---|---|
| Uniprot Accession: Q91XL6 | |
| Uniprot ID: Q91XL6_RAT | |
| Mapping: Chr 2, 118640277 - 118670170 | |
| Entrez Gene: 170911 | |
| Entrez MapView: |
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| RGD: 620916 | |
| +All IPI Database Cross References | |
| There are no ortholog records associated with this IPI entry. |
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Annotations for Pik3ca and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| phosphoinositide 3-kinase complex | C | ISS IEA | ||
| lamellipodium | C | ISS | ||
| protein binding | F | ISS | ||
| phosphotransferase activity, alcohol group as acceptor | F | IEA | ||
| insulin receptor substrate binding | F | ISS | ||
| 1-phosphatidylinositol-3-kinase activity | F | ISS ISS IEA | ||
| inositol or phosphatidylinositol kinase activity | F | IEA | ||
| protein kinase B signaling cascade | P | ISS | ||
| regulation of body size | P | ISS | ||
| negative regulation of apoptosis | P | ISS | ||
| glucose metabolic process | P | ISS | ||
| anti-apoptosis | P | ISS | ||
| protein amino acid phosphorylation | P | ISS | ||
| signal transduction | P | IEA |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (0)
There are no Mammalian Phenotype Ontology annotations for this protein in the database
Disease (0)
There are no Disease Ontology annotations for this protein in the database
Pathway (0)
There are no Pathway Ontology annotations for this protein in the database
KEGG Pathway (20)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| T cell receptor signaling pathway (04660) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Inositol phosphate metabolism (00562) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Phosphatidylinositol signaling system (04070) | Not present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute