IpiRecord: IPI00211817

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular region	C	NAS	IEA	ISS IEA
extracellular space	C		RCA	ISS IDA
serine-type endopeptidase activity	F		IEA IEA
receptor binding	F			ISS
hydrolase activity	F		IEA
protein C (activated) activity	F	TAS	IEA	TAS ISS IEA
calcium ion binding	F	IEA	IEA IEA	ISS IEA
peptidase activity	F	IEA	IEA	IEA
protein domain specific binding	F			ISS
phospholipid binding	F			ISS
negative regulation of coagulation	P			TAS
negative regulation of blood coagulation	P	TAS		ISS
negative regulation of inflammatory response	P			TAS
proteolysis	P	NAS	IEA	ISS ISS IEA
negative regulation of apoptosis	P	IMP	NAS	ISS IEA
blood coagulation	P	IEA	IEA IEA IEA	IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
muscle phenotype	MP		Un
nervous system phenotype	MP		Un
respiratory system phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
growth/size phenotype	MP		Un
life span-post-weaning/aging	MP		Un
liver/biliary system phenotype	MP		Un

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Venous Thrombosis	D			ISSISS
Protein C Deficiency	D			ISS
Thrombophilia	D			ISSISS
Thromboembolism	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
protein C anticoagulant pathway	W			TAS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway