IpiRecord: IPI00211841

IPI00211841 - Nfkbia, SIMILAR TO NF-KAPPAB INHIBITOR ALPHA.
Uniprot Accession: Q63746
Uniprot ID: IKBA_RAT
Mapping: Chr 6, 75729302 - 75732474
Entrez Gene: 25493
Entrez MapView: Geneprod
RGD: 3171
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6334)
Rat: Nfkbia, SIMILAR TO NF-KAPPAB INHIBITOR ALPHA.
Mouse: Nfkbia, NF-KAPPA-B INHIBITOR ALPHA.
Human: NFKBIA, NF-KAPPA-B INHIBITOR ALPHA.

Annotations for Nfkbia and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIDA IDA ISS ISS IEA 
cytosolCIEA IDA ISS IDA IEA 
nucleusCIDA IDA ISS ISS IEA 
protein complexCIDA 
nuclear localization sequence bindingFIPI ISS IEA 
heat shock protein bindingFIPI 
ubiquitin protein ligase bindingFIPI ISS IEA 
protein bindingFIPI IPI ISS IEA 
NF-kappaB bindingFIPI ISS IPI IEA 
lipopolysaccharide-mediated signaling pathwayPIEA IDA 
protein import into nucleus, translocationPIEA IDA ISS IEA 
apoptosisPTAS ISS 
cytoplasmic sequestering of NF-kappaBPNAS ISS 
negative regulation of Notch signaling pathwayPIEA IMP ISS IEA 
negative regulation of DNA bindingPNAS ISS 
response to lipopolysaccharidePIEA IDA 
negative regulation of myeloid cell differentiationPIEA IMP ISS IEA 
response to exogenous dsRNAPIEA IDA 
response to bacteriumPISS 
regulation of cell proliferationPIEA IDA ISS IEA 
regulation of NF-kappaB import into nucleusPNAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn Un Un
cellular phenotypeMPUn Un
lethality-embryonic/perinatalMPUn
immune system phenotypeMPUn Un Un Un
lethality-postnatalMPUn Un Un Un
normal phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un
growth/size phenotypeMPUn Un Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway