IpiRecord: IPI00211995

IPI00211995 - Limk2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2.
Uniprot Accession: P53670-1
Uniprot ID: LIMK2_RAT
Mapping: Chr 14, 83969282 - 84037218
Entrez Gene: 29524
Entrez MapView: Geneprod
RGD: 62056
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11973)
Rat: Limk2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2.
Mouse: Limk2, ISOFORM 1 OF LIM DOMAIN KINASE 2.
Mouse: Limk2, ISOFORM 3 OF LIM DOMAIN KINASE 2.
Mouse: Limk2, ISOFORM 2 OF LIM DOMAIN KINASE 2.
Mouse: Limk2, LIM MOTIF-CONTAINING PROTEIN KINASE 2.
Rat: Limk2, ISOFORM LIMK2B OF LIM DOMAIN KINASE 2.
Rat: Limk2, ISOFORM LIMK2C OF LIM DOMAIN KINASE 2.
Rat: Limk2, ISOFORM LIMK2D OF LIM DOMAIN KINASE 2.
Rat: Limk2, 71 KDA PROTEIN.
Rat: Limk2, 51 KDA PROTEIN.
Human: LIMK2, ISOFORM LIMK2A OF LIM DOMAIN KINASE 2.
Human: LIMK2, LIM DOMAIN KINASE 2 ISOFORM 1.
Human: LIMK2, ISOFORM LIMK2B OF LIM DOMAIN KINASE 2.

Annotations for Limk2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIDA IDA ISS ISS 
cytoplasmCIDA ISS ISS 
cis-Golgi networkCIDA ISS 
soluble fractionCIDA 
protein heterodimerization activityFIPI ISS 
metal ion bindingFIEA IEA 
ATP bindingFIEA IEA IEA 
protein-tyrosine kinase activityFIEA 
kinase activityFIEA 
protein serine/threonine kinase activityFIEA IEA TAS IDA ISS 
protein bindingFIEA IEA 
protein kinase activityFIEA IMP ISS 
transferase activityFIEA 
nucleotide bindingFIEA IEA 
zinc ion bindingFIEA IEA IEA 
spermatogenesisPIMP ISS 
protein amino acid phosphorylationPIEA IMP IDA ISS 
stress fiber formationPISS 
spermatid developmentPTAS 
focal adhesion formationPISS 
regulation of cytoskeleton organization and biogenesisPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
renal/urinary system phenotypeMPUn
reproductive system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Rho/Rac/Cdc42 mediated signaling pathwayWISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway