IPI report for IPI00213036

IpiRecord: IPI00213036

IPI00213036 - C4a, COMPLEMENT C4 PRECURSOR.
Uniprot Accession: P08649
Uniprot ID: CO4_RAT
Mapping: Chr 20, 4106165 - 4111993
Entrez Gene: 24233
Entrez MapView:
RGD: 620005
+All IPI Database Cross References UniProtKB/Swiss-Prot: P08649 UniProtKB/Swiss-Prot: CO4_RAT ENSEMBL: ENSRNOP00000000514 ENSEMBL: ENSRNOG00000000443 REFSEQ_PROVISIONAL: NP_113692 REFSEQ_PROVISIONAL: GI:29789265 UniParc: UPI0000127C53 RGD: 620005 Entrez Gene: 24233 UniGene: Rn.81052 InterPro: IPR009048 InterPro: IPR011626 InterPro: IPR002890 InterPro: IPR011625 InterPro: IPR000020 InterPro: IPR001840 InterPro: IPR001599 InterPro: IPR001134 InterPro: IPR008930 InterPro: IPR008993 Pfam: PF00207 Pfam: PF07678 Pfam: PF01835 Pfam: PF07703 Pfam: PF07677 Pfam: PF01821 Pfam: PF01759 PRINTS: PR00004 ProDom: PD003264 SMART: SM00104 SMART: SM00643 PROSITE: PS00477 PROSITE: PS01177 PROSITE: PS01178 PROSITE: PS50189 SUPERFAMILY: SSF49410 SUPERFAMILY: SSF47686 SUPERFAMILY: SSF48239 SUPERFAMILY: SSF50242 GENE3D: G3DSA:1.20.91.20 GENE3D: G3DSA:2.60.40.690

IPI00213036 - C4a, COMPLEMENT C4 PRECURSOR.

Uniprot Accession: P08649

Uniprot ID: CO4_RAT

Mapping: Chr 20, 4106165 - 4111993

Entrez Gene: 24233

Entrez MapView: Geneprod

RGD: 620005

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17788)
Rat: C4a, COMPLEMENT C4 PRECURSOR.
Human: C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.
Human: C4B, COMPLEMENT C4-B PRECURSOR.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_17788)

Rat: C4a, COMPLEMENT C4 PRECURSOR.

Human: C4B, COMPLEMENT COMPONENT 4B PREPROPROTEIN.

Human: C4B, COMPLEMENT C4-B PRECURSOR.

Annotations for C4a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Rat
extracellular region	C	IEA	IDA
molecular_function	F		ND
protein binding	F	IEA
endopeptidase inhibitor activity	F	IEA	IEA
complement activation, classical pathway	P	IEA	NAS
inflammatory response	P	IEA	NAS
complement activation	P	IEA	TAS ISS
innate immune response	P	IEA	IEA
positive regulation of smooth muscle contraction	P		NAS
immunoglobulin mediated immune response	P		ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
classical complement pathway	W			IMP

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway