IpiRecord: IPI00214207

IPI00214207 - Ppargc1a, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA.
Uniprot Accession: Q9QYK2
Uniprot ID: PRGC1_RAT
Mapping: Chr 14, 64278122 - 64371412
Entrez Gene: 83516
Entrez MapView: Geneprod
RGD: 620925
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11894)
Rat: Ppargc1a, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA.
Mouse: Ppargc1a, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA.
Mouse: Ppargc1a, CLONE:A830037N07 PRODUCT:HYPOTHETICAL PROTEIN, FULL INSERT SEQUENCE.
Mouse: Ppargc1a, 10 KDA PROTEIN.
Mouse: Ppargc1a, PPAR GAMMA COACTIVATOR VARIANT FORM.
Human: PPARGC1A, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA.

Annotations for Ppargc1a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIDA 
DNA-directed RNA polymerase II, core complexCTAS ISS 
nucleusCTAS IC ISS ISS IEA IDA 
receptor activityFIEA 
androgen receptor bindingFNAS ISS 
nucleotide bindingFIEA IEA IEA 
transcription activator activityFIDA ISS 
ligand-dependent nuclear receptor transcription coactivator activityFTAS ISS 
protein bindingFIPI ISS IEA 
nucleic acid bindingFRCA ISS 
RNA polymerase II transcription mediator activityFTAS ISS 
transcription factor bindingFTAS ISS 
transcription coactivator activityFIMP IDA ISS IEA 
DNA bindingFTAS IDA ISS ISS 
RNA bindingFTAS IEA ISS IEA 
fatty acid oxidationPNAS ISS 
androgen receptor signaling pathwayPNAS ISS 
digestionPTAS ISS 
positive regulation of histone acetylationPTAS ISS 
mitochondrion organization and biogenesisPNAS ISS IMP 
mRNA processingPTAS ISS 
gluconeogenesisPNAS ISS 
thermoregulationPTAS ISS 
positive regulation of transcriptionPIDA IDA ISS IEA 
protein stabilizationPTAS ISS 
brown fat cell differentiationPTAS ISS 
transcription initiation from RNA polymerase II promoterPTAS ISS 
cell glucose homeostasisPNAS ISS 
response to starvationPNAS ISS 
electron transportPIEA IDA ISS IEA 
protein complex assemblyPTAS ISS 
transcriptionPIEA IEA IEA 
regulation of transcription, DNA-dependentPIEA IEA 
RNA splicingPTAS ISS 
positive regulation of gluconeogenesisPTAS ISS TAS 
positive regulation of fatty acid oxidationPTAS ISS IMP 
cellular respirationPTAS ISS 
positive regulation of transcription, DNA-dependentPISS IMP 
positive regulation of transcription from RNA polymerase II promoterPIEA IGI 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
adipose tissue phenotypeMPUn Un
behavior/neurological phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un
lethality-postnatalMPUn
muscle phenotypeMPUn Un
nervous system phenotypeMPUn Un
respiratory system phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hearing/vestibular/ear phenotypeMPUn
liver/biliary system phenotypeMPUn
growth/size phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway