IpiRecord: IPI00214504

IPI00214504 - Ifng, INTERFERON GAMMA PRECURSOR.
Uniprot Accession: P01581
Uniprot ID: IFNG_RAT
Mapping: Chr 7, 57621754 - 57625792
Entrez Gene: 25712
Entrez MapView: Geneprod
RGD: 2866
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7047)
Rat: Ifng, INTERFERON GAMMA PRECURSOR.
Mouse: Ifng, INTERFERON GAMMA PRECURSOR.
Human: IFNG, INTERFERON GAMMA PRECURSOR.

Annotations for Ifng and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular regionCIEA IEA IMP IEA 
extracellular spaceCIEA IDA IDA IDA IDA IDA IDA ISS IEA 
transcription activator activityFISS 
cytokine activityFIEA IDA IDA IDA IDA TAS ISS IEA 
interferon-gamma receptor bindingFTAS IEA ISS IEA 
positive regulation of chemokine biosynthetic processPIEA IDA IMP ISS IEA 
defense response to bacteriumPIEA IDA ISS IEA 
antigen processing and presentationPIEA IDA ISS IEA 
response to virusPIEA IEA IEA 
regulation of transcriptionPIEA IDA ISS IEA 
positive regulation of interleukin-6 biosynthetic processPIEA IDA IMP ISS IEA 
positive regulation of interleukin-12 biosynthetic processPIEA IDA ISS IEA 
negative regulation of myelinationPIEA IDA IEA 
cell surface receptor linked signal transductionPTAS ISS 
immune responsePIEA 
regulation of cell growthPIEA IEA IEA 
neutrophil apoptosisPIEA IMP ISS IEA 
unfolded protein responsePIEA IDA IEA 
neutrophil chemotaxisPIEA IDA IMP ISS IEA 
negative regulation of cell proliferationPIDA 
cell motilityPTAS ISS 
positive regulation of interleukin-1 beta secretionPIEA IMP ISS IEA 
positive regulation of isotype switching to IgG isotypesPIEA IDA ISS IEA 
positive regulation of MHC class II biosynthetic processPIEA IDA ISS IEA 
cell-cell signalingPNR ISS 
inflammatory cell apoptosisPIEA IMP ISS IEA 
positive regulation of transcription, DNA-dependentPIEA IDA ISS IEA 
regulation of immune responsePIEA IDA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn Un
lethality-postnatalMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
tumorigenesisMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn
liver/biliary system phenotypeMPUn Un
no phenotypic analysisMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (7)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of autophagy (04140)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
TGF-beta signaling pathway (04350)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway