IpiRecord: IPI00215220

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytosol	C			IMP
cytoplasm	C	IEA	IDA	ISS
cysteine-type peptidase activity	F	IEA	IEA	IEA
peptidase activity	F		IDA IMP IMP	ISS
protein binding	F	IPI
phospholipase A2 activator activity	F			IMP
hydrolase activity	F		IEA
cyclin-dependent protein kinase inhibitor activity	F		IMP	ISS
caspase activity	F	IDA IEA	RCA IDA IDA IDA IDA IMP IDA IDA ISS	IEA ISS IDA IDA
DNA fragmentation during apoptosis	P		IMP	ISS
keratinocyte differentiation	P		IMP	ISS
induction of apoptosis by oxidative stress	P		IDA	ISS
intracellular signaling cascade	P			IMP
neuron apoptosis	P		IDA
T cell homeostasis	P		IMP	ISS
negative regulation of B cell proliferation	P		IMP	ISS
response to wounding	P		IDA	ISS
negative regulation of progression through cell cycle	P		IMP	ISS
neuron differentiation	P			IEP
induction of apoptosis via death domain receptors	P		IMP	ISS
B cell homeostasis	P		IMP	ISS
negative regulation of cyclin-dependent protein kinase activity	P		IMP	ISS
apoptosis	P	IEA	IMP IDA	IEA ISS
negative regulation of apoptosis	P	IGI	ISS
nuclear fragmentation during apoptosis	P	IMP
heart development	P		IGI	ISS
induction of apoptosis	P	TAS	IGI RCA IDA IDA IDA IMP IMP	TAS ISS
sensory perception of sound	P		IMP
response to UV	P		IGI	ISS
proteolysis	P	IDA IEA	RCA	IEA ISS IDA IDA
cell fate commitment	P		IMP	ISS
negative regulation of activated T cell proliferation	P		IMP	ISS
release of cytochrome c from mitochondria	P		IGI	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (22)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un
craniofacial phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un
immune system phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un
skeleton phenotype	MP		Un
lethality-postnatal	MP		Un Un
renal/urinary system phenotype	MP		Un
taste/olfaction phenotype	MP		Un
nervous system phenotype	MP		Un Un Un
respiratory system phenotype	MP		Un
vision/eye phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
reproductive system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un
growth/size phenotype	MP		Un
pigmentation phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (6)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
intrinsic apoptotic pathway	W			TAS
Parkinson disease pathway	W			IEA
programmed cell death pathway	W			TAS
Alzheimer disease pathway	W			IEA
mitogen activated protein kinase signaling pathway	W			IEA
Huntington disease pathway	W			IEA

KEGG Pathway (8)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Epithelial cell signaling in Helicobacter pylori infection (05120)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Huntington's disease (05040)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dentatorubropallidoluysian atrophy (DRPLA) (05050)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway