| IPI00215402 - Prkaa1, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1. | |
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| Uniprot Accession: P54645 | |
| Uniprot ID: AAPK1_RAT | |
| Mapping: Chr 2, 54327815 - 54360462 | |
| Entrez Gene: 65248 | |
| Entrez MapView: |
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| RGD: 3387 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2210) |
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| Rat: Prkaa1, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1. |
| Mouse: Prkaa1, PROTEIN KINASE, AMP-ACTIVATED, ALPHA 1 CATALYTIC SUBUNIT. |
| Human: PRKAA1, PRKAA1 PROTEIN. |
| Human: PRKAA1, PROTEIN KINASE, AMP-ACTIVATED, ALPHA 1 CATALYTIC SUBUNIT ISOFORM 2. |
| Human: PRKAA1, PROTEIN KINASE, AMP-ACTIVATED, ALPHA 1 CATALYTIC SUBUNIT ISOFORM 1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| intracellular | C | IC | ISS | |
| protein complex | C | IDA | ||
| AMP-activated protein kinase complex | C | IDA IMP | ||
| AMP-activated protein kinase activity | F | IDA IMP IMP IDA | ||
| kinase activity | F | IEA | ||
| protein kinase activity | F | IEA | ISS | |
| nucleotide binding | F | IEA | IEA | IEA |
| protein binding | F | IPI | ||
| metal ion binding | F | IEA | ||
| protein C-terminus binding | F | IPI | ||
| magnesium ion binding | F | IEA | IEA | IEA |
| ATP binding | F | IEA | IEA IEA | IDA IEA |
| cAMP-dependent protein kinase activity | F | NAS | ISS | |
| protein serine/threonine kinase activity | F | IEA | IEA IEA | IDA IEA |
| transferase activity | F | IEA | IEA | IEA |
| eukaryotic elongation factor-2 kinase activator activity | F | NAS | ||
| activation of MAPK activity | P | NAS | ISS | |
| fatty acid oxidation | P | IMP | IEA ISS | |
| positive regulation of glucose import | P | NAS | ||
| glucose metabolic process | P | IMP | IEA ISS | |
| sterol biosynthetic process | P | IEA | ||
| negative regulation of protein biosynthetic process | P | NAS | ||
| response to hypoxia | P | NAS | ISS | |
| protein amino acid phosphorylation | P | IEA TAS | IEA | IDA NAS IDA |
| lipid biosynthetic process | P | IEA | ||
| fatty acid biosynthetic process | P | IEA | IEA | IEA |
| positive regulation of cholesterol biosynthetic process | P | NAS | ISS | |
| cholesterol biosynthetic process | P | IEA | IEA | IEA |
| positive regulation of anti-apoptosis | P | NAS | ISS | |
| signal transduction | P | TAS | ISS | |
| steroid biosynthetic process | P | IEA | ||
| positive regulation of gluconeogenesis | P | NAS | ||
| negative regulation of glucosylceramide biosynthetic process | P | NAS | ISS | |
| positive regulation of fatty acid oxidation | P | NAS | ||
| protein heterooligomerization | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| muscle phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nicotinate and nicotinamide metabolic pathway | W | IEA | ||
| inositol phosphate metabolic pathway | W | IEA | ||
| adenosine monophosphate-activated protein kinase (AMPK) signaling pathway | W | IDAISSISS | ||
| starch and sucrose metabolic pathway | W | IEA | ||
| benzoate degradation pathway via CoA ligation | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Regulation of autophagy (04140) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |