IPI report for IPI00231499

IpiRecord: IPI00231499

IPI00231499 - Abcc3, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 3.
Uniprot Accession: O88563
Uniprot ID: MRP3_RAT
Mapping: Chr 10, 82987107 - 83030751
Entrez Gene: 140668
Entrez MapView:
RGD: 71101
+All IPI Database Cross References UniProtKB/Swiss-Prot: O88563 UniProtKB/Swiss-Prot: MRP3_RAT ENSEMBL: ENSRNOP00000003977 ENSEMBL: ENSRNOG00000002948 REFSEQ_PROVISIONAL: NP_542148 REFSEQ_PROVISIONAL: GI:18034783 UniParc: UPI000016797E RGD: 71101 Entrez Gene: 140668 UniGene: Rn.205054 InterPro: IPR003593 InterPro: IPR011527 InterPro: IPR001140 InterPro: IPR003439 InterPro: IPR005292 Pfam: PF00664 Pfam: PF00005 ProDom: PD000006 SMART: SM00382 TIGRFAMs: TIGR00957 PROSITE: PS50929 PROSITE: PS00211 PROSITE: PS50893

IPI00231499 - Abcc3, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 3.

Uniprot Accession: O88563

Uniprot ID: MRP3_RAT

Mapping: Chr 10, 82987107 - 83030751

Entrez Gene: 140668

Entrez MapView: Geneprod

RGD: 71101

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9750)
Rat: Abcc3, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 3.
Mouse: Abcc3, (CFTR/MRP), MEMBER 3, FULL INSERT SEQUENCE.
Rat: Abcc3, MULTIDRUG RESISTANCE PROTEIN 3.
Human: ABCC3, ISOFORM 3 OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.
Human: ABCC3, ISOFORM 3B OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.
Human: ABCC3, ISOFORM 3S1 OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.
Human: ABCC3, ISOFORM 3A OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.
Human: ABCC3, 8 KDA PROTEIN.
Human: ABCC3, ABCC3 PROTEIN.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9750)

Rat: Abcc3, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 3.

Mouse: Abcc3, (CFTR/MRP), MEMBER 3, FULL INSERT SEQUENCE.

Rat: Abcc3, MULTIDRUG RESISTANCE PROTEIN 3.

Human: ABCC3, ISOFORM 3 OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.

Human: ABCC3, ISOFORM 3B OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.

Human: ABCC3, ISOFORM 3S1 OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.

Human: ABCC3, ISOFORM 3A OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2.

Human: ABCC3, 8 KDA PROTEIN.

Human: ABCC3, ABCC3 PROTEIN.

Annotations for Abcc3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C		IDA	ISS ISS
membrane fraction	C			ISS
membrane	C			IEA
integral to membrane	C	IEA		IEA
organic anion transmembrane transporter activity	F			ISS
ATPase activity	F			IEA
transporter activity	F			IEA
nucleotide binding	F		IEA	IEA
ATPase activity, coupled to transmembrane movement of substances	F	IEA	ISS	ISS IDA
ATP binding	F	IEA	IEA	ISS IEA
transport	P	IEA		ISS IEA
canalicular bile acid transport	P		ISS	IDA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Jaundice, Chronic Idiopathic	D			IEP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
multidrug resistance-associated protein mediated transport pathway	W			ISS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
ABC transporters - General (02010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway