IpiRecord: IPI00231574

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
vesicle membrane	C		IDA	ISS
cytoplasm	C		IDA	ISS
membrane	C		IDA	ISS
phosphoprotein binding	F			IPI
phosphotyrosine binding	F			IPI
insulin receptor substrate binding	F			IPI
protein binding	F		IPI IPI IPI IPI IPI	ISS
receptor activity	F		IEA
SH3/SH2 adaptor activity	F		IPI	ISS
MAPKKK cascade	P		IGI	ISS
Ras protein signal transduction	P		TAS	TAS ISS
intracellular signaling cascade	P	IEA	IEA
protein heterooligomerization	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
immune system phenotype	MP		Un
normal phenotype	MP		Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
tumorigenesis	MP		Un
cleft palate	N			ISS
perinatal lethality	N			ISS
increased tumor incidence	N			ISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (5)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
insulin-like growth factor signaling pathway	W			IMP
insulin signaling pathway	W			IDA
mitogen activated protein kinase signaling pathway	W			IEA
JAK-STAT signaling pathway	W			IEA
Huntington disease pathway	W			IEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
GnRH signaling pathway (04912)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Huntington's disease (05040)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Gap junction (04540)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dorso-ventral axis formation (04320)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway