IpiRecord: IPI00231733

IPI00231733 - Gnai1, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT.
Uniprot Accession: P10824
Uniprot ID: GNAI1_RAT
Mapping: Chr 4, 12489156 - 12493730
Entrez Gene: 25686
Entrez MapView: Geneprod
RGD: 2713
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4259)
Rat: Gnai1, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT.
Mouse: Gnai1, GUANINE NUCLEOTIDE BINDING PROTEIN, ALPHA INHIBITING 1.
Human: GNAI1, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT.
Human: GNAI1, 41 KDA PROTEIN.

Annotations for Gnai1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
lipid raftCIDA 
plasma membraneCTAS 
cytoplasmCIEA 
Golgi apparatusCIEA 
heterotrimeric G-protein complexCTAS TAS 
GTP bindingFIEA IEA 
GTPase activityFTAS TAS ISS 
protein bindingFIPI 
signal transducer activityFIEA IEA 
guanyl nucleotide bindingFIEA 
nucleotide bindingFIEA IEA 
negative regulation of synaptic transmissionPIMP 
signal transductionPIEA IEA 
G-protein coupled receptor protein signaling pathwayPIEA TAS IMP ISS ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
G protein signaling pathway via Galphai familyWIMP
orexin/hypocretin signaling pathway through the orexin/hypocretin receptor 2WIMP

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway