IpiRecord: IPI00231785

IPI00231785 - Cacna1a, 1A.
Uniprot Accession: P54282-2
Uniprot ID: CAC1A_RAT
Mapping: Chr 19, 25188220 - 25424495
Entrez Gene: 25398
Entrez MapView: Geneprod
RGD: 2244
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13891)
Rat: Cacna1a, 29 KDA PROTEIN.
Mouse: Cacna1a, VOLTAGE-DEPENDENT P/Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A.
Mouse: Cacna1a, ALPHA 1A SUBUNIT, FULL INSERT SEQUENCE.
Rat: Cacna1a, CLASS A CALCIUM CHANNEL VARIANT RIA-I (FRAGMENT).
Rat: Cacna1a, CLASS A CALCIUM CHANNEL VARIANT RIA-II (FRAGMENT).
Rat: Cacna1a, 1A.
Rat: Cacna1a, 1A.
Rat: Cacna1a, 163 KDA PROTEIN.
Human: CACNA1A, SUBUNIT ALPHA-1A.
Human: CACNA1A, ALPHA-1A.
Human: CACNA1A, SUBUNIT ALPHA-1A.
Human: CACNA1A, ALPHA-1A.
Human: CACNA1A, ALPHA1A-VOLTAGE-DEPENDENT CALCIUM CHANNEL.
Human: CACNA1A, SUBUNIT ALPHA-1A.
Human: CACNA1A, ALPHA-1A.
Human: CACNA1A, CALCIUM CHANNEL, ALPHA 1A SUBUNIT ISOFORM 2.

Annotations for Cacna1a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA IEA 
plasma membraneCIMP IDA 
voltage-gated calcium channel complexCIEA IDA TAS ISS IDA IEA 
dendriteCIDA 
cell somaCIDA 
nucleusCISS 
integral to membraneCNAS IEA RCA ISS IEA 
perikaryonCIDA 
DNA bindingFRCA ISS 
voltage-gated calcium channel activityFIDA IEA IMP IMP IDA IMP IMP IMP IDA TAS ISS IDA IEA 
protein bindingFIPI IPI ISS 
calcium channel activityFIEA 
voltage-gated ion channel activityFIEA IEA 
calcium ion bindingFIEA IEA IEA 
ion channel activityFIEA IEA IEA IEA 
high voltage-gated calcium channel activityFIMP IMP IMP IGI IMP IMP IMP IMP IMP IMP 
central nervous system neuron differentiationPIMP 
vestibular nucleus developmentPIMP 
calcium ion-dependent exocytosisPIMP 
negative regulation of neuron apoptosisPIMP IMP 
gamma-aminobutyric acid secretionPIMP 
neurotransmitter metabolic processPIMP IMP IMP 
behavioral response to painPIMP 
cellular chloride ion homeostasisPIMP IMP 
thyroid hormone metabolic processPIMP 
dendrite morphogenesisPIMP IMP IMP 
regulation of axonogenesisPIMP 
sulfur amino acid metabolic processPIMP 
musculoskeletal movement, spinal reflex actionPIMP 
cerebellar molecular layer developmentPIMP 
glucose metabolic processPIMP 
negative regulation of hormone biosynthetic processPIMP 
synaptic transmissionPIMP IMP IMP IMP 
regulation of calcium ion-dependent exocytosisPIDA 
cerebellar Purkinje cell layer developmentPIMP 
calcium ion transportPIEA IMP IMP IMP IMP IDA ISS IEA 
regulation of membrane potentialPIMP IMP IMP IMP IMP IMP IMP 
synaptic transmission, GABAergicPIMP 
cerebellum maturationPIMP 
receptor clusteringPIMP 
neuromuscular synaptic transmissionPIMP 
regulation of transcription, DNA-dependentPISS 
transmission of nerve impulsePIMP IMP IMP 
rhythmic synaptic transmissionPIMP 
gamma-aminobutyric acid signaling pathwayPIMP 
regulation of balancePIMP 
adult walking behaviorPIMP IMP IMP IMP IGI IMP IMP IMP IMP IMP IMP IGI 
regulation of acetylcholine secretionPIMP IMP 
membrane depolarizationPIMP IMP IMP 
calcium ion-dependent exocytosis of neurotransmitterPIMP 
synaptic transmission, glutamatergicPIMP IMP 
cerebellar Purkinje cell differentiationPIMP IMP IMP 
nerve-nerve synaptic transmissionPIMP 
cell growthPIMP 
transportPIEA 
elevation of cytosolic calcium ion concentrationPIDA RCA IDA ISS 
neurological processPIMP IMP 
response to painPIMP 
neuromuscular processPIGI IMP 
ion transportPIEA IEA IEA IEA 
hormone metabolic processPIMP IMP 
synaptogenesisPIMP IMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
behavior/neurological phenotypeMPUn Un Un Un Un Un Un
immune system phenotypeMPUn
lethality-postnatalMPUn Un
muscle phenotypeMPUn Un Un Un
nervous system phenotypeMPUn Un Un Un Un Un Un
normal phenotypeMPUn
reproductive system phenotypeMPUn
hematopoietic system phenotypeMPUn
life span-post-weaning/agingMPUn Un
growth/size phenotypeMPUn Un Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Taste transduction (04742)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway