IpiRecord: IPI00231829

IPI00231829 - Arg2, ARGINASE-2, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: O08701
Uniprot ID: ARGI2_RAT
Mapping: Chr 6, 101901653 - 101928282
Entrez Gene: 29215
Entrez MapView: Geneprod
RGD: 2151
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6356)
Rat: Arg2, ARGINASE-2, MITOCHONDRIAL PRECURSOR.
Mouse: Arg2, ARGINASE-2, MITOCHONDRIAL PRECURSOR.
Human: ARG2, ARGINASE-2, MITOCHONDRIAL PRECURSOR.

Annotations for Arg2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrionCTAS ISS IMP ISS IDA IDA 
hydrolase activityFIEA IEA IEA 
arginase activityFTAS ISS IDA ISS IDA IDA 
metal ion bindingFIEA IEA IEA IEA 
protein bindingFISS IPI IPI 
nitric-oxide synthase bindingFIPI 
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidinesFIEA 
manganese ion bindingFIEA IEA IEA 
nitric oxide biosynthetic processPTAS ISS 
urea cyclePIEA IEA IEA 
arginine catabolic process to ornithinePTAS 
striated muscle contractionPIEA IMP ISS IEA 
arginine metabolic processPIEA IMP 
arginine catabolic processPIEA IEA 
regulation of nitric oxide biosynthetic processPIEP 
negative regulation of nitric-oxide synthase activityPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
SepsisDIEP
Liver Cirrhosis, ExperimentalDIEP
HypertensionDIEP

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
arginine and proline metabolic pathwayWIEA
pathway of urea cycle and metabolism of amino groupsWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arginine and proline metabolism (00330)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Urea cycle and metabolism of amino groups (00220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway