| IPI00231848 - Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR. | |
|---|---|
| Uniprot Accession: Q6P6T8 | |
| Uniprot ID: Q6P6T8_RAT | |
| Mapping: Chr 2, 227107576 - 227194674 | |
| Entrez Gene: 25313 | |
| Entrez MapView: |
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| RGD: 2542 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2831) |
|---|
| Rat: Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR. |
| Mouse: Egf, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR. |
| Human: EGF, PRO-EPIDERMAL GROWTH FACTOR PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | IEA | IDA IDA | ISS IEA |
| nucleus | C | NR | ISS | |
| membrane | C | IEA IEA | IEA | |
| integral to membrane | C | IEA | RCA | ISS IEA |
| extracellular region | C | IC | ISS | |
| plasma membrane | C | TAS | ISS | |
| calcium ion binding | F | IEA | IEA | IEA |
| protein binding | F | IPI | ISS IEA | |
| epidermal growth factor receptor activating ligand activity | F | TAS | ISS | |
| growth factor activity | F | IDA | ISS | ISS IEA |
| epidermal growth factor receptor binding | F | TAS | ||
| branching morphogenesis of a tube | P | IEA | IDA | ISS IEA |
| positive regulation of mitosis | P | IDA | ||
| protein kinase cascade | P | TAS | ||
| positive regulation of epidermal growth factor receptor activity | P | IDA | ||
| regulation of peptidyl-tyrosine phosphorylation | P | IEA | IDA | ISS IEA |
| peptidyl-tyrosine phosphorylation | P | IDA | ISS | |
| positive regulation of granule cell precursor proliferation | P | IEA | IDA | IEA |
| chromosome organization and biogenesis (sensu Eukaryota) | P | TAS | ISS | |
| angiogenesis | P | IDA | ||
| regulation of protein secretion | P | IMP | ||
| DNA replication | P | TAS | ISS | |
| positive regulation of cell proliferation | P | IGI ISS IDA IDA IGI IGI | ISS ISS | |
| epidermal growth factor receptor signaling pathway | P | IEA | IDA IGI | ISS ISS IEA |
| activation of MAPKK activity | P | IEA | IDA | ISS IEA |
| positive regulation of phosphorylation | P | IDA | ||
| activation of MAPK activity | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| touch/vibrissae phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| epidermal growth factor/neuregulin signaling pathway | W | IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |