| IPI00231922 - Pdgfb, SIMILAR TO PLATELET-DERIVED GROWTH FACTOR B CHAIN PRECURSOR. | |
|---|---|
| Uniprot Accession: Q05028 | |
| Uniprot ID: PDGFB_RAT | |
| Mapping: Chr 7, 118245297 - 118261626 | |
| Entrez Gene: 24628 | |
| Entrez MapView: |
|
| RGD: 3283 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7331) |
|---|
| Rat: Pdgfb, SIMILAR TO PLATELET-DERIVED GROWTH FACTOR B CHAIN PRECURSOR. |
| Mouse: Pdgfb, PLATELET-DERIVED GROWTH FACTOR B CHAIN PRECURSOR. |
| Mouse: Pdgfb, PLATELET DERIVED GROWTH FACTOR, B POLYPEPTIDE. |
| Rat: Pdgfb, PDGF PROTEIN (FRAGMENT). |
| Human: PDGFB, PLATELET-DERIVED GROWTH FACTOR B CHAIN PRECURSOR. |
| Human: PDGFB, PLATELET-DERIVED GROWTH FACTOR BETA ISOFORM 2, PREPROPROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | RCA | ISS | |
| extracellular region | C | NAS | ISS | |
| membrane | C | IEA | IEA | IEA |
| cytoplasm | C | IDA | ||
| growth factor activity | F | IEA | IEA IEA | IEA |
| platelet-derived growth factor receptor binding | F | NAS | IMP ISS | |
| regulation of peptidyl-tyrosine phosphorylation | P | IDA | ISS | |
| transforming growth factor beta receptor signaling pathway | P | IMP | ||
| response to hypoxia | P | IEP | ||
| regulation of progression through cell cycle | P | IEA | IEA IEA | IEA |
| DNA replication | P | IEP | ||
| negative regulation of cell migration | P | IGI | ||
| cell proliferation | P | IEA | IEA | |
| actin cytoskeleton organization and biogenesis | P | IDA | ISS | |
| response to wounding | P | NAS | ISS | |
| cellular process | P | IEA | ||
| cell projection biogenesis | P | IDA | ISS | |
| positive regulation of endothelial cell proliferation | P | IGI | ||
| substrate-bound cell migration | P | IDA | ISS | |
| regulation of cell proliferation | P | IEP | ||
| cell growth | P | IEP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un | ||
| immune system phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| muscle phenotype | MP | Un Un Un | ||
| renal/urinary system phenotype | MP | Un Un Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un Un Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| reproductive system phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| no phenotypic analysis | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| pigmentation phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hypertension, Pulmonary | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| transforming growth factor-beta signaling pathway | W | IMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |