| IPI00287199 - Abca1, ATP-BINDING CASSETTE 1. | |
|---|---|
| Uniprot Accession: Q80ZB2 | |
| Uniprot ID: Q80ZB2_RAT | |
| Mapping: Chr 5, 70493552 - 70598070 | |
| Entrez Gene: 313210 | |
| Entrez MapView: |
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| RGD: 631344 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5419) |
|---|
| Rat: Abca1, ATP-BINDING CASSETTE 1. |
| Mouse: Abca1, ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1. |
| Mouse: Abca1, ATP-BINDING CASSETTE 1, SUB-FAMILY A, MEMBER 1. |
| Human: ABCA1, ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1. |
| Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A. |
| Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A MEMBER 1. |
| Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A (ABC1), MEMBER 1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| membrane | C | IEA | IEA | |
| integral to plasma membrane | C | NAS | IDA | ISS ISS |
| integral to membrane | C | RCA | ISS | |
| membrane fraction | C | TAS | ISS | |
| plasma membrane | C | IDA | IDA | |
| Golgi apparatus | C | IDA | ISS | |
| intracellular membrane-bound organelle | C | IDA | ISS | |
| ATPase activity, coupled to transmembrane movement of substances | F | IDA TAS | ||
| high-density lipoprotein binding | F | IPI | ||
| ATP binding | F | NAS IEA IEA | IEA IEA | IEA ISS |
| protein binding | F | IPI | IPI | ISS IPI |
| nucleoside-triphosphatase activity | F | IEA | ||
| ATPase activity | F | IEA | IEA | IEA |
| sterol transporter activity | F | TAS | ISS | |
| anion transmembrane transporter activity | F | TAS | ISS | |
| nucleotide binding | F | IEA | IEA IEA | IEA |
| response to nutrient | P | IEP | ||
| phagocytosis, engulfment | P | IMP | ISS | |
| cholesterol metabolic process | P | NAS | IDA | ISS ISS |
| steroid metabolic process | P | IEA | ||
| peptide secretion | P | IMP | ||
| phospholipid translocation | P | IMP | ISS | |
| lipoprotein biosynthetic process | P | IMP IMP | IMP ISS | |
| phospholipid transport | P | IDA TAS | ||
| transport | P | TAS | IEA | ISS |
| lipid metabolic process | P | IEA | ||
| cholesterol efflux | P | IMP IMP IDA | ||
| cholesterol transport | P | IDA | IMP IDA ISS | |
| response to drug | P | IEP | ||
| lipoprotein metabolic process | P | IMP | ||
| protein amino acid lipidation | P | IMP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un Un Un | ||
| immune system phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| liver/biliary system phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| lethality-postnatal | MP | Un Un | ||
| renal/urinary system phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un | ||
| respiratory system phenotype | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| reproductive system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un Un | ||
| decreased circulating HDL cholesterol level | N | ISS | ||
| increased cholesterol absorption | N | ISS | ||
| increased circulating HDL cholesterol level | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Obesity | D | ISS | ||
| Glomerulonephritis, Membranous | D | IEP | ||
| Metabolic Syndrome X | D | ISS | ||
| Fatty Liver | D | IEP | ||
| Carcinoma, Hepatocellular | D | IEP | ||
| Hypolipoproteinemia | D | ISS | ||
| Tangier Disease | D | ISS | ||
| Hyperlipidemia | D | IEP | ||
| Coronary Arteriosclerosis | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| reverse cholesterol transport pathway | W | ISSTAS | ||
| altered reverse cholesterol transport pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |