IpiRecord: IPI00287199

IPI00287199 - Abca1, ATP-BINDING CASSETTE 1.
Uniprot Accession: Q80ZB2
Uniprot ID: Q80ZB2_RAT
Mapping: Chr 5, 70493552 - 70598070
Entrez Gene: 313210
Entrez MapView: Geneprod
RGD: 631344
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5419)
Rat: Abca1, ATP-BINDING CASSETTE 1.
Mouse: Abca1, ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1.
Mouse: Abca1, ATP-BINDING CASSETTE 1, SUB-FAMILY A, MEMBER 1.
Human: ABCA1, ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1.
Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A.
Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A MEMBER 1.
Human: ABCA1, ATP-BINDING CASSETTE, SUB-FAMILY A (ABC1), MEMBER 1.

Annotations for Abca1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA 
integral to plasma membraneCNAS IDA ISS ISS 
integral to membraneCRCA ISS 
membrane fractionCTAS ISS 
plasma membraneCIDA IDA 
Golgi apparatusCIDA ISS 
intracellular membrane-bound organelleCIDA ISS 
ATPase activity, coupled to transmembrane movement of substancesFIDA TAS 
high-density lipoprotein bindingFIPI 
ATP bindingFNAS IEA IEA IEA IEA IEA ISS 
protein bindingFIPI IPI ISS IPI 
nucleoside-triphosphatase activityFIEA 
ATPase activityFIEA IEA IEA 
sterol transporter activityFTAS ISS 
anion transmembrane transporter activityFTAS ISS 
nucleotide bindingFIEA IEA IEA IEA 
response to nutrientPIEP 
phagocytosis, engulfmentPIMP ISS 
cholesterol metabolic processPNAS IDA ISS ISS 
steroid metabolic processPIEA 
peptide secretionPIMP 
phospholipid translocationPIMP ISS 
lipoprotein biosynthetic processPIMP IMP IMP ISS 
phospholipid transportPIDA TAS 
transportPTAS IEA ISS 
lipid metabolic processPIEA 
cholesterol effluxPIMP IMP IDA 
cholesterol transportPIDA IMP IDA ISS 
response to drugPIEP 
lipoprotein metabolic processPIMP 
protein amino acid lipidationPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un Un Un Un
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
liver/biliary system phenotypeMPUn
muscle phenotypeMPUn
lethality-postnatalMPUn Un
renal/urinary system phenotypeMPUn Un
hematopoietic system phenotypeMPUn Un Un
respiratory system phenotypeMPUn Un
cardiovascular system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn Un
reproductive system phenotypeMPUn Un
growth/size phenotypeMPUn Un
decreased circulating HDL cholesterol levelNISS
increased cholesterol absorptionNISS
increased circulating HDL cholesterol levelNISS

Disease (9)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
ObesityDISS
Glomerulonephritis, MembranousDIEP
Metabolic Syndrome XDISS
Fatty LiverDIEP
Carcinoma, HepatocellularDIEP
HypolipoproteinemiaDISS
Tangier DiseaseDISS
HyperlipidemiaDIEP
Coronary ArteriosclerosisDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
reverse cholesterol transport pathwayWISSTAS
altered reverse cholesterol transport pathwayWISS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway