| IPI00324110 - Apaf1, APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. | |
|---|---|
| Uniprot Accession: Q8VI66 | |
| Uniprot ID: Q8VI66_RAT | |
| Mapping: Chr 7, 27934653 - 28018255 | |
| Entrez Gene: 78963 | |
| Entrez MapView: |
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| RGD: 620575 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6910) |
|---|
| Rat: Apaf1, APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Mouse: Apaf1, ISOFORM 1 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Mouse: Apaf1, APAF1 PROTEIN. |
| Mouse: Apaf1, ISOFORM 2 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 1 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 2 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 3 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 4 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 5 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, ISOFORM 6 OF APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. |
| Human: APAF1, 10 KDA PROTEIN. |
| Human: APAF1, 3 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | ||
| cytosol | C | TAS IDA | ISS ISS | |
| membrane | C | IEA | ||
| soluble fraction | C | IDA | IEA ISS | |
| nucleus | C | IDA | IEA ISS | |
| intracellular | C | IEA | IEA | |
| caspase activator activity | F | ISS | ||
| protein binding | F | IEA | ISS | |
| ATP binding | F | IEA IEA | IEA | |
| apoptotic protease activator activity | F | IPI | IEA ISS | |
| dipeptidyl-peptidase IV activity | F | IEA | ||
| peptidase activity | F | IEA | ||
| identical protein binding | F | IPI | IEA ISS | |
| nucleotide binding | F | IEA | IEA ISS | |
| caspase activation via cytochrome c | P | ISS | ||
| defense response | P | IEA | IEA | |
| forebrain development | P | IMP | IEA ISS ISS | |
| induction of apoptosis | P | IDA | ||
| nervous system development | P | ISS | ||
| regulation of apoptosis | P | IEA | IEA ISS | |
| proteolysis | P | IEA | ||
| caspase activation | P | TAS | ISS | |
| neural tube closure | P | IMP IMP | IEA ISS ISS | |
| brain development | P | IMP | ISS ISS | |
| multicellular organismal development | P | IMP | IEA ISS | |
| apoptosis | P | IEA IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un Un | ||
| craniofacial phenotype | MP | Un Un Un | ||
| behavior/neurological phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| lethality-postnatal | MP | Un | ||
| skeleton phenotype | MP | Un Un Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| hearing/vestibular/ear phenotype | MP | Un Un | ||
| tumorigenesis | MP | Un | ||
| vision/eye phenotype | MP | Un Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| limbs/digits/tail phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| abnormal apoptosis | N | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |