| IPI00324168 - Gsk3b, GLYCOGEN SYNTHASE KINASE-3 BETA. | |
|---|---|
| Uniprot Accession: P18266 | |
| Uniprot ID: GSK3B_RAT | |
| Mapping: Chr 11, 64284731 - 64428698 | |
| Entrez Gene: 84027 | |
| Entrez MapView: |
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| RGD: 70982 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10506) |
|---|
| Rat: Gsk3b, GLYCOGEN SYNTHASE KINASE-3 BETA. |
| Mouse: Gsk3b, GLYCOGEN SYNTHASE KINASE-3 BETA. |
| Mouse: Gsk3b, 48 KDA PROTEIN. |
| Human: GSK3B, ISOFORM 1 OF GLYCOGEN SYNTHASE KINASE-3 BETA. |
| Human: GSK3B, ISOFORM 2 OF GLYCOGEN SYNTHASE KINASE-3 BETA. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytosol | C | IDA | ISS ISS IEA | |
| cytoplasm | C | ISS | TAS | |
| nucleus | C | IDA ISS | ISS ISS IEA | |
| nucleotide binding | F | IEA | IEA | |
| p53 binding | F | ISS | ||
| kinase activity | F | IEA | ||
| protein binding | F | IPI | IDA ISS ISS | |
| glycogen synthase kinase 3 activity | F | ISS ISS | TAS IDA ISS | |
| protein kinase activity | F | IDA | ISS | |
| ATP binding | F | IEA IEA | IEA | |
| protein serine/threonine kinase activity | F | IEA IEA | IEA | |
| NF-kappaB binding | F | ISS | ||
| tau-protein kinase activity | F | IDA | ISS IEA | |
| transferase activity | F | IEA | IEA | |
| protein kinase binding | F | IPI | ||
| beta-catenin binding | F | IPI | ISS IEA | |
| negative regulation of transcription, DNA-dependent | P | IDA | ||
| intracellular signaling cascade | P | ISS | ||
| protein export from nucleus | P | IDA | ISS IEA | |
| peptidyl-serine phosphorylation | P | ISS | ||
| fat cell differentiation | P | IDA | ISS IEA | |
| establishment and/or maintenance of cell polarity | P | IDA | ||
| cell proliferation | P | TAS | ISS | |
| protein amino acid phosphorylation | P | IDA IDA IDA | ISS IEA | |
| Wnt receptor signaling pathway | P | IGI | IEA | |
| response to stress | P | IDA | ISS IEA | |
| induction of apoptosis | P | IDA TAS | ||
| glycogen metabolic process | P | ISS | ||
| establishment of cell polarity | P | IDA | ||
| ER overload response | P | ISS IDA | ||
| negative regulation of apoptosis | P | ISS | ||
| re-entry into mitotic cell cycle | P | IDA | ISS IEA | |
| anti-apoptosis | P | IMP | ISS IEA | |
| organ morphogenesis | P | IMP | ISS IEA | |
| positive regulation of protein export from nucleus | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un Un | ||
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| skeleton phenotype | MP | Un Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| normal phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| embryonic lethality | N | ISS | ||
| neurodegeneration | N | ISSIED | ||
| liver degeneration | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| ?? | B | ISSISSISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| long term depression | W | IMP | ||
| canonical Wnt signaling pathway | W | IDA | ||
| Alzheimer disease pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hedgehog signaling pathway (04340) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |