IpiRecord: IPI00324177

IPI00324177 - Itpr2, INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Uniprot Accession: Q6W3E4
Uniprot ID: Q6W3E4_RAT
Mapping: Chr 4, 183679958 - 184065884
Entrez Gene: 81678
Entrez MapView: Geneprod
RGD: 69649
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5109)
Rat: Itpr2, INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Mouse: Itpr2, ISOFORM 2 OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Mouse: Itpr2, ISOFORM 3 OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Mouse: Itpr2, ISOFORM 1 OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Mouse: Itpr2, 93 KDA PROTEIN.
Mouse: Itpr2, 16 KDA PROTEIN.
Mouse: Itpr2, 73 KDA PROTEIN.
Rat: Itpr2, 303 KDA PROTEIN.
Rat: Itpr2, 182 KDA PROTEIN.
Human: ITPR2, ISOFORM LONG OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Human: ITPR2, ISOFORM SHORT OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2.
Human: ITPR2, 16 KDA PROTEIN.
Human: ITPR2, PROTEIN.

Annotations for Itpr2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCISS 
membraneCIEA RCA ISS IEA 
integral to membraneCRCA ISS IEA 
endoplasmic reticulumCIEA RCA ISS ISS IEA 
inositol 1,4,5-triphosphate-sensitive calcium-release channel activityFIEA RCA ISS IEA 
receptor activityFRCA ISS IEA 
calcium channel activityFRCA ISS IEA 
inositol-1,4,5-triphosphate receptor activityFISS 
ion channel activityFRCA ISS IEA 
calcium ion bindingFIEA IEA 
calcium ion transmembrane transporter activityFISS 
cation channel activityFRCA ISS 
calcium ion transportPIEA RCA ISS IEA 
cation transportPRCA ISS 
transportPIEA 
ion transportPRCA ISS IEA 
signal transductionPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
digestive/alimentary phenotypeMPUn
normal phenotypeMPUn
cardiovascular system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn
no phenotypic analysisMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway